Method to fabricate hollow microneedle arrays

Kravitz, Stanley H; Ingersoll, David; Schmidt, Carrie; Flemming, Jeb

Title: Method to fabricate hollow microneedle arrays

Patent · Tue Nov 07 00:00:00 EST 2006

OSTI ID:908048

Kravitz, Stanley H ^[1]; Ingersoll, David ^[2]; Schmidt, Carrie ^[3]; Flemming, Jeb ^[2]

Placitas, NM
Albuquerque, NM
Los Lunas, NM

An inexpensive and rapid method for fabricating arrays of hollow microneedles uses a photoetchable glass. Furthermore, the glass hollow microneedle array can be used to form a negative mold for replicating microneedles in biocompatible polymers or metals. These microneedle arrays can be used to extract fluids from plants or animals. Glucose transport through these hollow microneedles arrays has been found to be orders of magnitude more rapid than natural diffusion.

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Research Organization:: Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

Sponsoring Organization:: USDOE

DOE Contract Number:: AC04-94AL85000

Assignee:: Sandia Corporation (Albuquerque, NM)

Patent Number(s):: 7,132,054

Application Number:: 10/936,360

OSTI ID:: 908048

Country of Publication:: United States

Language:: English

References (11)

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3D microstructuring inside photosensitive glass by use of a femtosecond laser for lab-on-chip applications Cheng, Ya; Sugioka, Koji; Masuda, Masashi High-Power Lasers and Applications, SPIE Proceedings https://doi.org/10.1117/12.479539	conference	July 2003
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Side-opened out-of-plane microneedles for microfluidic transdermal liquid transfer Griss, P.; Stemme, G. Journal of Microelectromechanical Systems, Vol. 12, Issue 3 https://doi.org/10.1109/JMEMS.2003.809959	journal	June 2003
Photoetchable glass for microsystems: tips for atomic force microscopy Dietrich, T. R.; Abraham, M.; Diebel, J. Journal of Micromechanics and Microengineering, Vol. 3, Issue 4 https://doi.org/10.1088/0960-1317/3/4/004	journal	December 1993
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