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Title: Synthesis of 2H- and 13C-substituted dithanes

Patent ·
OSTI ID:875140

The present invention is directed to labeled compounds, [2-.sup.13 C]dithiane wherein the .sup.13 C atom is directly bonded to one or two deuterium atoms. The present invention is also directed to processes of preparing [2-.sup.13 C]dithiane wherein the .sup.13 C atom is directly bonded to one or two deuterium atoms. The present invention is also directed to labeled compounds, e.g., [.sup.2 H.sub.1-2, .sup.13 C]methanol (arylthio)-, acetates wherein the .sup.13 C atom is directly bonded to exactly one or two deuterium atoms.

Research Organization:
Los Alamos National Laboratory (LANL), Los Alamos, NM (United States)
DOE Contract Number:
W-7405-ENG-36
Assignee:
The Regents of the University of California (Los Alamos, NM)
Patent Number(s):
US 6541671
OSTI ID:
875140
Country of Publication:
United States
Language:
English

References (4)

Stereoelectronic effects in the gas-phase. 2. Negative ion reactions of 1,3-dithianes and 1,3-dithiane 1-oxides journal September 1989
The use of metalloids (-SiMe3,-SnR3) as protected carbanions journal January 1981
9-Phenylfluorene: a powerful labeling agent journal July 2001
Protonic and conformational equilibriums of 1,3-dithiaalkanes and their congeners in highly acidic media journal December 1979