Cytochrome b5 gene and protein of Candida tropicalis and methods relating thereto
Patent
·
OSTI ID:874978
- Fort Thomas, KY
- Westfield, IN
- Cincinnati, OH
A novel gene has been isolated which encodes cytochrome b5 (CYTb5) protein of the .omega.-hydroxylase complex of C. tropicalis 20336. Vectors including this gene, and transformed host cells are provided. Methods of increasing the production of a CYTb5 protein are also provided which involve transforming a host cell with a gene encoding this protein and culturing the cells. Methods of increasing the production of a dicarboxylic acid are also provided which involve increasing in the host cell the number of genes encoding this protein.
- Research Organization:
- GE CORPORATE R & D
- DOE Contract Number:
- FC36-95GO10099
- Assignee:
- Cognis Corporation (Gulph Mills, PA)
- Patent Number(s):
- US 6503734
- OSTI ID:
- 874978
- Country of Publication:
- United States
- Language:
- English
Genetic Analysis of Cytochrome b5 from Arachidonic Acid-Producing Fungus, Mortierella alpina 1S-4: Cloning, RNA Editing and Expression of the Gene in Escherichia coli, and Purification and Characterization of the Gene Product
|
journal | June 1999 |
Isolation and characterization of cytochrome b5 from Candida tropicalis grown on alkane
|
journal | December 1982 |
Cloning and characterization of a yeast cytochrome b5-encoding gene which suppresses ketoconazole hypersensitivity in a NADPH-P-450 reductase-deficient strain
|
journal | May 1994 |
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OSTI ID:874978
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