Water-soluble luminescent quantum dots and biomolecular conjugates thereof and related compositions and method of use

Nie, Shuming; Chan, Warren C. W.; Emory, Steven R

Title: Water-soluble luminescent quantum dots and biomolecular conjugates thereof and related compositions and method of use

Patent · Tue Jan 01 00:00:00 EST 2002

OSTI ID:874824

Nie, Shuming ^[1]; Chan, Warren C. W. ^[1]; Emory, Steven R ^[2]

Bloomington, IN
Los Alamos, NM

The present invention provides a water-soluble luminescent quantum dot, a biomolecular conjugate thereof and a composition comprising such a quantum dot or conjugate. Additionally, the present invention provides a method of obtaining a luminescent quantum dot, a method of making a biomolecular conjugate thereof, and methods of using a biomolecular conjugate for ultrasensitive nonisotopic detection in vitro and in vivo.

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Research Organization:: Indiana Univ., Bloomington, IN (United States)

DOE Contract Number:: FG02-98ER14873

Assignee:: Advanced Research and Technology Institute, Inc. (Indianapolis, IN)

Patent Number(s):: US 6468808

OSTI ID:: 874824

Country of Publication:: United States

Language:: English

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water-soluble
luminescent
quantum
dots
biomolecular
conjugates
related
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method
provides
dot
conjugate
composition
comprising
additionally
obtaining
methods
ultrasensitive
nonisotopic
detection
vitro
vivo
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Title: Water-soluble luminescent quantum dots and biomolecular conjugates thereof and related compositions and method of use

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References (33)

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