Salicylamide-lanthanide complexes for use as luminescent markers

Raymond, Kenneth N; Petoud, Stephane; Cohen, Seth; Xu, Jide

Title: Salicylamide-lanthanide complexes for use as luminescent markers

Patent · Tue Jan 01 00:00:00 EST 2002

OSTI ID:874518

Raymond, Kenneth N ^[1]; Petoud, Stephane ^[1]; Cohen, Seth ^[2]; Xu, Jide ^[1]

Berkeley, CA
West Lake Village, CA

The present invention provides luminescent lanthanide metal chelates comprising a metal ion of the lanthanide series and a complexing agent comprising at least one salicylamidyl moiety. Also provided are probes incorporating the salicylamidyl ligands of the invention and methods utilizing the ligands of the invention and probes comprising the ligands of the invention.

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Research Organization:: Lawrence Berkeley National Laboratory (LBNL), Berkeley, CA (United States)

DOE Contract Number:: AC03-76SF00098

Assignee:: The Regents of the University of California (Oakland, CA)

Patent Number(s):: US 6406297

OSTI ID:: 874518

Country of Publication:: United States

Language:: English

References (16)

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Synthesis, Time-Resolved Luminescence, NMR Spectroscopy, Circular Dichroism and Circularly Polarised Luminescence Studies of Enantiopure Macrocyclic Lanthanide Tetraamide Complexes Dickins, Rachel S.; Howard, Judith A. K.; Maupin, Christine L. Chemistry - A European Journal, Vol. 5, Issue 3, p. 1095-1105 https://doi.org/10.1002/(SICI)1521-3765(19990301)5:3<1095::AID-CHEM1095>3.0.CO;2-C	journal	March 1999
Development of luminescent lanthanide chelate labels for diagnostic assays Hemmilä, Ilkka; Mukkala, Veli-Matti; Takalo, Harri Journal of Alloys and Compounds, Vol. 249, Issue 1-2, p. 158-162 https://doi.org/10.1016/S0925-8388(96)02834-4	journal	March 1997
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Towards materials with planned properties: dinuclear f-f helicates and d-f non-covalent podates based on benzimidazole-pyridine binding units Bünzli, Jean-Claude G.; Petoud, Stéphane; Piguet, Claude Journal of Alloys and Compounds, Vol. 249, Issue 1-2, p. 14-24 https://doi.org/10.1016/S0925-8388(96)02519-4	journal	March 1997
Lifetime- and Color-Tailored Fluorophores in the Micro- to Millisecond Time Regime Chen, Jiyan; Selvin, Paul R. Journal of the American Chemical Society, Vol. 122, Issue 4, p. 657-660 https://doi.org/10.1021/ja9913986	journal	February 2000
Time-resolved fluorescence of a new europium-chelate complex: demonstration of highly sensitive detection of protein and DNA samples Saha, Ashis K.; Kross, Kathryn; Kloszewski, Edmond D. Journal of the American Chemical Society, Vol. 115, Issue 23, p. 11032-11033 https://doi.org/10.1021/ja00076a088	journal	November 1993
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Terbium and Rhodamine as Labels in a Homogeneous Time-resolved Fluorometric Energy Transfer Assay of the β Subunit of Human Chorionic Gonadotropin in Serum Blomberg, Kaj; Hurskainen, Pertti; Hemmilä, Ilkka Clinical Chemistry, Vol. 45, Issue 6 https://doi.org/10.1093/clinchem/45.6.855	journal	June 1999
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Homogeneous Time-Resolved Il-2–Il-2rα Assay Using Fluorescence Resonance Energy Transfer Stenroos, Karolina; Hurskainen, Pertti; Eriksson, Susann Cytokine, Vol. 10, Issue 7 https://doi.org/10.1006/cyto.1997.0321	journal	July 1998

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salicylamide-lanthanide
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moiety
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probes
incorporating
ligands
methods
utilizing
complexing agent
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lanthanide metal
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Title: Salicylamide-lanthanide complexes for use as luminescent markers

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