Doped colorimetric assay liposomes

Charych, Deborah; Stevens, Raymond C

Title: Doped colorimetric assay liposomes

Patent · Mon Jan 01 00:00:00 EST 2001

OSTI ID:873536

Charych, Deborah ^[1]; Stevens, Raymond C ^[1]

Albany, CA

The present invention provides compositions comprising colorimetric assay liposomes. The present invention also provides methods for producing colorimetric liposomes and calorimetric liposome assay systems. In preferred embodiments, these calorimetric liposome systems provide high levels of sensitivity through the use of dopant molecules. As these dopants allow the controlled destabilization of the liposome structure, upon exposure of the doped liposomes to analyte(s) of interest, the indicator color change is facilitated and more easily recognized.

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Research Organization:: Lawrence Berkeley National Laboratory (LBNL), Berkeley, CA (United States)

DOE Contract Number:: AC03-76SF00098

Assignee:: Reagents of University of California (CA)

Patent Number(s):: US 6183772

OSTI ID:: 873536

Country of Publication:: United States

Language:: English

References (33)

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Title: Doped colorimetric assay liposomes

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References (33)

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