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Title: Three-dimensional scanning confocal laser microscope

Patent ·
OSTI ID:872185
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A confocal microscope for generating an image of a sample includes a first scanning element for scanning a light beam along a first axis, and a second scanning element for scanning the light beam at a predetermined amplitude along a second axis perpendicular to the first axis. A third scanning element scans the light beam at a predetermined amplitude along a third axis perpendicular to an imaging plane defined by the first and second axes. The second and third scanning element are synchronized to scan at the same frequency. The second and third predetermined amplitudes are percentages of their maximum amplitudes. A selector determines the second and third predetermined amplitudes such that the sum of the percentages is equal to one-hundred percent.

Research Organization:
The General Hospital Corp., Boston, MA (United States)
Sponsoring Organization:
USDOE
DOE Contract Number:
FG02-91ER61229
Assignee:
The General Hospital Corp. (Boston, MA)
Patent Number(s):
5,880,880
Application Number:
08/683,607
OSTI ID:
872185
Resource Relation:
Patent File Date: 1996 Jul 15
Country of Publication:
United States
Language:
English

References (8)

Morphometry of human epidermis in vivo by real-time confocal microscopy journal November 1993
Optics for laser rasters journal January 1984
Confocal scanning laser ophthalmoscope journal January 1987
The Optics of Human Skin journal July 1981
Flying spot TV ophthalmoscope journal January 1980
In vivo spatio-temporal visualization of the human skin by real-time confocal microscopy journal January 1994
In vivo imaging of human teeth and skin using real-time confocal microscopy: In vivo confocal microscopy journal January 1991
In vivo Vision of the Human Skin with the Tandem Scanning Microscope journal January 1993

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