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Title: Biotin compounds for targetting tumors and sites of infection

Patent ·
OSTI ID:871360

Novel biotin amide analogs that are useful for targeting therapeutic and imaging agents to sites of infection and tumors in vivo are disclosed.

Research Organization:
Massachusetts Inst. of Technology (MIT), Cambridge, MA (United States)
DOE Contract Number:
FG02-86ER60460
Assignee:
JMDE Trust (Newton, MA)
Patent Number(s):
US 5716594
OSTI ID:
871360
Country of Publication:
United States
Language:
English

References (3)

Avidin binding of radiolabeled biotin derivatives. journal January 1988
An approach to the targeted attachment of peptides and proteins to solid supports. journal October 1976
99mTc Labeled Biotin Conjugate in a Tumor“Pretargeting” Approach with Monoclonal Antibodies journal November 1992