Multivariate classification of infrared spectra of cell and tissue samples

Haaland, David M; Jones, Howland D. T.; Thomas, Edward V

Title: Multivariate classification of infrared spectra of cell and tissue samples

Patent · Wed Jan 01 00:00:00 EST 1997

OSTI ID:870800

Haaland, David M ^[1]; Jones, Howland D. T. ^[1]; Thomas, Edward V ^[1]

Albuquerque, NM

Multivariate classification techniques are applied to spectra from cell and tissue samples irradiated with infrared radiation to determine if the samples are normal or abnormal (cancerous). Mid and near infrared radiation can be used for in vivo and in vitro classifications using at least different wavelengths.

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Research Organization:: AT&T

DOE Contract Number:: AC04-76DP00789

Assignee:: Sandia Corporation (Albuquerque, NM)

Patent Number(s):: US 5596992

OSTI ID:: 870800

Country of Publication:: United States

Language:: English

References (16)

Comparison of multivariate calibration methods for quantitative spectral analysis Thomas, Edward V.; Haaland, David M. Analytical Chemistry, Vol. 62, Issue 10 https://doi.org/10.1021/ac00209a024	journal	May 1990
Human colorectal cancers display abnormal Fourier-transform infrared spectra. Rigas, B.; Morgello, S.; Goldman, I. S. Proceedings of the National Academy of Sciences, Vol. 87, Issue 20 https://doi.org/10.1073/pnas.87.20.8140	journal	October 1990
Analytical infrared spectral differences between human normal and leukaemic cells (CLL) — I Benedetti, Enzo; Papineschi, Federico; Vergamini, Piergiorgio Leukemia Research, Vol. 8, Issue 3 https://doi.org/10.1016/0145-2126(84)90089-4	journal	January 1984
Alteration in molecular structure of cytoskeleton proteins in griseofulvin-treated mouse liver: A pressure tuning infrared spectroscopy study Cadrin, Monique; French, Samuel W.; Wong, Patrick T. T. Experimental and Molecular Pathology, Vol. 55, Issue 2 https://doi.org/10.1016/0014-4800(91)90050-8	journal	October 1991
Multivariate Calibration Methods Applied to Quantitative FT-IR Analyses Haaland, David M. Practical Fourier Transform Infrared Spectroscopy, p. 395-468 https://doi.org/10.1016/B978-0-12-254125-4.50013-6	book	January 1990
Infrared Spectra of Microtome Sections of Human Colon Tissues Wong, Patrick T. T.; Rigas, Basil Applied Spectroscopy, Vol. 44, Issue 10 https://doi.org/10.1366/0003702904417481	journal	December 1990
FT-IR analysis of single human normal and leukemic lymphocytes Benedetti, Enzo; Vergamini, Piergiorgio; Spremolla, Giuliano Mikrochimica Acta, Vol. 94, Issue 1-6 https://doi.org/10.1007/BF01205856	journal	January 1988
Materials Characterization Using Factor Analysis of FT-IR Spectra. Part 2: Mathematical and Statistical Considerations Fredericks, Peter M.; Lee, James B.; Osborn, Paul R. Applied Spectroscopy, Vol. 39, Issue 2 https://doi.org/10.1366/0003702854249006	journal	March 1985
A New Approach to the Study of Human Solid Tumor Cells by Means of FT-IR Microspectroscopy Benedetti, Enzo; Teodori, Laura; Trinca, Maria Luisa Applied Spectroscopy, Vol. 44, Issue 8 https://doi.org/10.1366/000370290789619621	journal	September 1990
Partial least-squares method for spectrofluorimetric analysis of mixtures of humic acid and lignin sulfonate Lindberg, Walter.; Persson, Jan-Aake.; Wold, Svante. Analytical Chemistry, Vol. 55, Issue 4 https://doi.org/10.1021/ac00255a014	journal	April 1983
Materials Characterization Using Factor Analysis of FT-IR Spectra. Part 1: Results Fredericks, Peter M.; Lee, James B.; Osborn, Paul R. Applied Spectroscopy, Vol. 39, Issue 2 https://doi.org/10.1366/0003702854248999	journal	March 1985
Phosphodiester Stretching Bands in the Infrared Spectra of Human Tissues and Cultured Cells Wong, P. T. T.; Papavassiliou, E. D.; Rigas, B. Applied Spectroscopy, Vol. 45, Issue 9 https://doi.org/10.1366/0003702914335580	journal	November 1991
Multivariate calibration applied to the quantitative analysis of infrared spectra Haaland, David M. Luebeck - DL tentative, SPIE Proceedings https://doi.org/10.1117/12.56281	conference	March 1992
Partial least-squares methods for spectral analyses. 1. Relation to other quantitative calibration methods and the extraction of qualitative information Haaland, David M.; Thomas, Edward V. Analytical Chemistry, Vol. 60, Issue 11 https://doi.org/10.1021/ac00162a020	journal	June 1988
Infrared Microspectroscopy Of Pathologic Tissue O'Leary, Timothy J.; Engler, Walter F.; Ventre, Kathleen M. Intl Conf on Fourier and Computerized Infrared Spectroscopy, SPIE Proceedings https://doi.org/10.1117/12.969588	conference	December 1989
Partial least-squares methods for spectral analyses. 2. Application to simulated and glass spectral data Haaland, David M.; Thomas, Edward V. Analytical Chemistry, Vol. 60, Issue 11 https://doi.org/10.1021/ac00162a021	journal	June 1988

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Related Subjects

multivariate
classification
infrared
spectra
cell
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techniques
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irradiated
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determine
normal
abnormal
cancerous
mid
near
vivo
vitro
classifications
wavelengths
tissue sample
near infrared
infrared radiation
tissue samples
multivariate classification
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Title: Multivariate classification of infrared spectra of cell and tissue samples

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References (16)

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