Noise suppressing capillary separation system
Patent
·
OSTI ID:870536
- Ames, IA
- Norwich, NY
A noise-suppressing capillary separation system for detecting the real-time presence or concentration of an analyte in a sample is provided. The system contains a capillary separation means through which the analyte is moved, a coherent light source that generates a beam which is split into a reference beam and a sample beam that irradiate the capillary, and a detector for detecting the reference beam and the sample beam light that transmits through the capillary. The laser beam is of a wavelength effective to be absorbed by a chromophore in the capillary. The system includes a noise suppressing system to improve performance and accuracy without signal averaging or multiple scans.
- Research Organization:
- Ames Laboratory (AMES), Ames, IA; Iowa State Univ., Ames, IA (United States)
- DOE Contract Number:
- W-7405-ENG-82
- Assignee:
- Iowa State University Research Foundation, Inc. (Ames, IA)
- Patent Number(s):
- US 5540825
- Application Number:
- 08/406,714
- OSTI ID:
- 870536
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
noise
suppressing
capillary
separation
noise-suppressing
detecting
real-time
presence
concentration
analyte
sample
provided
contains
means
moved
coherent
light
source
generates
beam
split
reference
irradiate
detector
transmits
laser
wavelength
effective
absorbed
chromophore
improve
performance
accuracy
signal
averaging
multiple
scans
reference beam
light source
laser beam
coherent light
sample beam
separation means
wavelength effective
beam light
capillary separation
improve performance
suppressing capillary
/204/73/356/
suppressing
capillary
separation
noise-suppressing
detecting
real-time
presence
concentration
analyte
sample
provided
contains
means
moved
coherent
light
source
generates
beam
split
reference
irradiate
detector
transmits
laser
wavelength
effective
absorbed
chromophore
improve
performance
accuracy
signal
averaging
multiple
scans
reference beam
light source
laser beam
coherent light
sample beam
separation means
wavelength effective
beam light
capillary separation
improve performance
suppressing capillary
/204/73/356/