Loading and conjugating cavity biostructures

Patent · Tue Aug 22 00:00:00 EDT 1995

OSTI ID:870039

Hainfeld, James F ^[1]

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1. Shoreham, NY

Methods for the preparation and use of a biological delivery system are disclosed. The method of preparation includes the loading of a non-biological material into a biostructure having a load-bearing structure. The method also includes the removal of some of the biostructure's contents and the loading of a non-biological material into the biostructure. The biostructure is biologically compatible with the host, and preferably is derived from the host, the host's species or a related species. The loaded biostructure is used directly, or it can be targeted to specific cells, tissues and/or organs within a host. The targeted biostructure can be used to deliver the non-biological material to a specified tissue, organ or cell within a host for diagnostic, therapeutic or other purposes.

• Research Organization: Associated Universities, Inc., Upton, NY (United States)
• DOE Contract Number: AC02-76CH00016
• Assignee: Associated Universities, Inc. (Washington, DC)
• Patent Number(s): US 5443813
• Application Number: 07/711,208
• OSTI ID: 870039
• Country of Publication: United States
• Language: English

Related Subjects

loading
conjugating
cavity
biostructures
methods
preparation
biological
delivery
disclosed
method
non-biological
material
biostructure
load-bearing
structure
removal
contents
biologically
compatible
host
preferably
derived
species
related
loaded
directly
targeted
specific
cells
tissues
organs
deliver
specified
tissue
organ
cell
diagnostic
therapeutic
purposes
non-biological material
specific cells
biological material
cavity biostructures
bearing structure
biological delivery
conjugating cavity
load-bearing structure
/424/530/