Method for immunodiagnostic detection of dioxins at low concentrations

Patent · Sun Jan 01 00:00:00 EST 1995

OSTI ID:869959

Vanderlaan, Martin ^[1]; Stanker, Larry H ^[2]; Watkins, Bruce E ^[2]; Petrovic, Peter ^[3]; Gorbach, Siegbert ^[4]

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1. Danville, CA
2. Livermore, CA
3. Hochheim am Main, DE
4. Eppstein/Ts., DE

A method is described for the use of monoclonal antibodies in a sensitive immunoassay for halogenated dioxins and dibenzofurans in industrial samples which contain impurities. Appropriate sample preparation and selective enzyme amplification of the immunoassay sensitivity permits detection of dioxin contaminants in industrial or environmental samples at concentrations in the range of a few parts per trillion.

• Research Organization: Lawrence Livermore National Laboratory (LLNL), Livermore, CA (United States)
• DOE Contract Number: W-7405-ENG-48
• Assignee: Regents of University of California (Oakland, CA)
• Patent Number(s): US 5429925
• OSTI ID: 869959
• Country of Publication: United States
• Language: English

Related Subjects

method
immunodiagnostic
detection
dioxins
concentrations
described
monoclonal
antibodies
sensitive
immunoassay
halogenated
dibenzofurans
industrial
samples
contain
impurities
appropriate
sample
preparation
selective
enzyme
amplification
sensitivity
permits
dioxin
contaminants
environmental
range
trillion
permits detection
environmental sample
sample preparation
monoclonal antibodies
environmental samples
sensitive immunoassay
/435/436/