Synthesis of alpha-amino acids

Patent · Sat Jan 01 00:00:00 EST 1983

OSTI ID:864503

Davis, Jr., Jefferson W. ^[1]

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1. (San Francisco, CA)

A method for synthesizing alpha amino acids proceeding through novel intermediates of the formulas: R.sub.1 R.sub.2 C(OSOCl)CN, R.sub.1 R.sub.2 C(Cl)CN and [R.sub.1 R.sub.2 C(CN)O].sub.2 SO wherein R.sub.1 and R.sub.2 are each selected from hydrogen monovalent substituted and unsubstituted hydrocarbon radicals of 1 to 12 carbon atoms. The use of these intermediates allows the synthesis steps to be exothermic and results in an overall synthesis method which is faster than the synthesis methods of the prior art.

• Research Organization: Lawrence Livermore National Laboratory (LLNL), Livermore, CA (United States)
• DOE Contract Number: W-7405-ENG-48
• Assignee: United States of America as represented by United States (Washington, DC)
• Patent Number(s): US 4375555
• OSTI ID: 864503
• Country of Publication: United States
• Language: English

Related Subjects

synthesis
alpha-amino
acids
method
synthesizing
alpha
amino
proceeding
novel
intermediates
formulas
osocl
cn
selected
hydrogen
monovalent
substituted
unsubstituted
hydrocarbon
radicals
12
carbon
atoms
allows
steps
exothermic
results
overall
faster
methods
prior
amino acid
carbon atoms
amino acids
carbon atom
synthesis steps
synthesizing alpha
unsubstituted hydrocarbon
alpha amino
alpha-amino acids
novel intermediates
overall synthesis
monovalent substituted
synthesis method
hydrocarbon radical
hydrocarbon radicals
hydrogen monovalent
intermediates allows
-amino acid
/999/