.sup.123m Te-Labeled biochemicals and method of preparation
Patent
·
OSTI ID:863621
- (Oak Ridge, TN)
A novel class of .sup.123m Te-labeled steroids and amino acids is provided by the method of reacting a .sup.123m Te symmetric diorgano ditelluride with a hydride reducing agent and a source of alkali metal ions to form an alkali metal organo telluride. The alkali metal organo telluride is reacted with a primary halogenated steroidal side chain, amino acid, or amino acid precursor such as hydantoin. The novel compounds are useful as biological tracers and as organal imaging agents.
- Research Organization:
- Oak Ridge National Laboratory (ORNL), Oak Ridge, TN (United States)
- Assignee:
- United States of America as represented by United States (Washington, DC)
- Patent Number(s):
- US 4215045
- OSTI ID:
- 863621
- Country of Publication:
- United States
- Language:
- English
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· J. Med. Chem.; (United States)
·
OSTI ID:863621
Related Subjects
123m
te-labeled
biochemicals
method
preparation
novel
steroids
amino
acids
provided
reacting
symmetric
diorgano
ditelluride
hydride
reducing
agent
source
alkali
metal
form
organo
telluride
reacted
primary
halogenated
steroidal
chain
acid
precursor
hydantoin
compounds
useful
biological
tracers
organal
imaging
agents
biological tracer
imaging agents
amino acid
alkali metal
reducing agent
amino acids
novel compounds
imaging agent
novel compound
/999/376/
te-labeled
biochemicals
method
preparation
novel
steroids
amino
acids
provided
reacting
symmetric
diorgano
ditelluride
hydride
reducing
agent
source
alkali
metal
form
organo
telluride
reacted
primary
halogenated
steroidal
chain
acid
precursor
hydantoin
compounds
useful
biological
tracers
organal
imaging
agents
biological tracer
imaging agents
amino acid
alkali metal
reducing agent
amino acids
novel compounds
imaging agent
novel compound
/999/376/