NMR structure of hypothetical protein MG354 from Mycoplasmagenitalium

Journal Article · Tue Apr 12 00:00:00 EDT 2005 · Proteins: Structure, Function and Bioinformatics

DOI:https://doi.org/10.1002/prot.20495· OSTI ID:862072

Pelton, Jeffrey G; Shi, Jianxia; Yokotoa, Hisao; Kim, Rosalind; Wemmer, David E

Mycoplasma genitalium (Mg) and M. pneumoniae (Mp) are human pathogens with two of the smallest genomes sequenced to date ({approx} 480 and 680 genes, respectively). The Berkeley Structural Genomics Center is determining representative structures for gene products in these organisms, helping to understand the set of protein folds needed to sustain this minimal organism. The protein coded by gene MG354 (gi3844938) from M. genitalium has a relatively unique sequence, related only to MPN530 from M. pneumoniae (68% identity, coverage 99%) and MGA{_}0870 from the avian pathogen M. gallisepticum (23% identity, coverage 94%), has no homologue with a determined structure, and no functional annotations.

• Research Organization: Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States)
• Sponsoring Organization: USDOE. Office of Management Budget and Evaluation; NationalInstitutes of Health Grant 5P50GM62412-03
• DOE Contract Number: DE-AC02-05CH11231
• OSTI ID: 862072
• Report Number(s): LBNL-57272; R&D Project: 864D4C; BnR: 400412000; TRN: US200602%%43
• Journal Information: Proteins: Structure, Function and Bioinformatics, Vol. 61, Issue 3; Related Information: Journal Publication Date: 11/15/2005
• Country of Publication: United States
• Language: English

Related Subjects

59 BASIC BIOLOGICAL SCIENCES
37 INORGANIC
ORGANIC
PHYSICAL AND ANALYTICAL CHEMISTRY
FUNCTIONALS
GENES
MYCOPLASMA
PATHOGENS
PROTEINS