Volume visualization of multiple alignment of genomic DNA
Genomes of hundreds of species have been sequenced to date and many more are being sequenced. As more and more sequence data sets become available, and as the challenge of comparing these massive ''billion basepair DNA sequences'' becomes substantial, so does the need for more powerful tools supporting the exploration of these data sets. Similarity score data used to compare aligned DNA sequences is inherently one-dimensional. One-dimensional (1D) representations of these data sets do not effectively utilize screen real estate. We present a technique to arrange 1D data in 3D space to allow us to apply state-of-the-art interactive volume visualization techniques for data exploration. We provide results for aligned DNA sequence data and compare it with traditional 1D line plots. Our technique, coupled with 1D line plots, results in effective multiresolution visualization of very large aligned sequence data sets.
- Research Organization:
- Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States)
- Sponsoring Organization:
- USDOE. Laboratory Directed Research Development; National Science Foundation ACI 9624034 and ACI 9982251, National Institutes of Health P20 MH60975-06A2, National Partnership for Advanced Computational Infrastructure, Information Technology Research Grant (US)
- DOE Contract Number:
- AC03-76SF00098
- OSTI ID:
- 828565
- Report Number(s):
- LBNL-55386; R&D Project: 365971; TRN: US200427%%473
- Resource Relation:
- Conference: IEEE Symposium on Information Visualization, Austin, TX (US), 10/10/2004--10/12/2004; Other Information: PBD: 1 May 2004
- Country of Publication:
- United States
- Language:
- English
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