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Title: Monte Carol-Based Dosimetry of Beta-Emitters for Intravascular Brachytherapy

Abstract

Monte Carlo simulations for radiation dosimetry and the experimental verifications of the simulations have been developed for the treatment geometry of intravascular brachytherapy, a form of radionuclide therapy for occluded coronary disease (restenosis). Monte Carlo code, MCNP4C, has been used to calculate the radiation dose from the encapsulated array of B-emitting seeds (Sr/Y-source train). Solid water phantoms have been fabricated to measure the dose on the radiochromic films that were exposed to the beta source train for both linear and curved coronary vessel geometries. While the dose difference for the 5-degree curved vessel at the prescription point of f+2.0 mm is within the 10% guideline set by the AAPM, however, the difference increased dramatically to 16.85% for the 10-degree case which requires additional adjustment for the acceptable dosimetry planning. The experimental dose measurements agree well with the simulation results

Authors:
Publication Date:
Research Org.:
Purdue Research Foundation (US)
Sponsoring Org.:
(US)
OSTI Identifier:
798524
Report Number(s):
DOE/NEER/PURDUE-C03-02
TRN: US200216%%217
DOE Contract Number:  
FG07-99ID13782
Resource Type:
Technical Report
Resource Relation:
Other Information: PBD: 25 Jun 2002
Country of Publication:
United States
Language:
English
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; BETA SOURCES; DISEASES; DOSIMETRY; GEOMETRY; PHANTOMS; PLANNING; RADIATION DOSES; RADIOISOTOPES; RECOMMENDATIONS; SEEDS; SIMULATION; THERAPY; WATER; INTRAVASCULAR BRACHYTHERAPY, RADIOCHROMIC FILM DOSIMETRY, MONTE CARLO SIMULATIONS

Citation Formats

Choi, C K. Monte Carol-Based Dosimetry of Beta-Emitters for Intravascular Brachytherapy. United States: N. p., 2002. Web. doi:10.2172/798524.
Choi, C K. Monte Carol-Based Dosimetry of Beta-Emitters for Intravascular Brachytherapy. United States. https://doi.org/10.2172/798524
Choi, C K. 2002. "Monte Carol-Based Dosimetry of Beta-Emitters for Intravascular Brachytherapy". United States. https://doi.org/10.2172/798524. https://www.osti.gov/servlets/purl/798524.
@article{osti_798524,
title = {Monte Carol-Based Dosimetry of Beta-Emitters for Intravascular Brachytherapy},
author = {Choi, C K},
abstractNote = {Monte Carlo simulations for radiation dosimetry and the experimental verifications of the simulations have been developed for the treatment geometry of intravascular brachytherapy, a form of radionuclide therapy for occluded coronary disease (restenosis). Monte Carlo code, MCNP4C, has been used to calculate the radiation dose from the encapsulated array of B-emitting seeds (Sr/Y-source train). Solid water phantoms have been fabricated to measure the dose on the radiochromic films that were exposed to the beta source train for both linear and curved coronary vessel geometries. While the dose difference for the 5-degree curved vessel at the prescription point of f+2.0 mm is within the 10% guideline set by the AAPM, however, the difference increased dramatically to 16.85% for the 10-degree case which requires additional adjustment for the acceptable dosimetry planning. The experimental dose measurements agree well with the simulation results},
doi = {10.2172/798524},
url = {https://www.osti.gov/biblio/798524}, journal = {},
number = ,
volume = ,
place = {United States},
year = {Tue Jun 25 00:00:00 EDT 2002},
month = {Tue Jun 25 00:00:00 EDT 2002}
}