Monte Carol-Based Dosimetry of Beta-Emitters for Intravascular Brachytherapy
Abstract
Monte Carlo simulations for radiation dosimetry and the experimental verifications of the simulations have been developed for the treatment geometry of intravascular brachytherapy, a form of radionuclide therapy for occluded coronary disease (restenosis). Monte Carlo code, MCNP4C, has been used to calculate the radiation dose from the encapsulated array of B-emitting seeds (Sr/Y-source train). Solid water phantoms have been fabricated to measure the dose on the radiochromic films that were exposed to the beta source train for both linear and curved coronary vessel geometries. While the dose difference for the 5-degree curved vessel at the prescription point of f+2.0 mm is within the 10% guideline set by the AAPM, however, the difference increased dramatically to 16.85% for the 10-degree case which requires additional adjustment for the acceptable dosimetry planning. The experimental dose measurements agree well with the simulation results
- Authors:
- Publication Date:
- Research Org.:
- Purdue Research Foundation (US)
- Sponsoring Org.:
- (US)
- OSTI Identifier:
- 798524
- Report Number(s):
- DOE/NEER/PURDUE-C03-02
TRN: US200216%%217
- DOE Contract Number:
- FG07-99ID13782
- Resource Type:
- Technical Report
- Resource Relation:
- Other Information: PBD: 25 Jun 2002
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 62 RADIOLOGY AND NUCLEAR MEDICINE; BETA SOURCES; DISEASES; DOSIMETRY; GEOMETRY; PHANTOMS; PLANNING; RADIATION DOSES; RADIOISOTOPES; RECOMMENDATIONS; SEEDS; SIMULATION; THERAPY; WATER; INTRAVASCULAR BRACHYTHERAPY, RADIOCHROMIC FILM DOSIMETRY, MONTE CARLO SIMULATIONS
Citation Formats
Choi, C K. Monte Carol-Based Dosimetry of Beta-Emitters for Intravascular Brachytherapy. United States: N. p., 2002.
Web. doi:10.2172/798524.
Choi, C K. Monte Carol-Based Dosimetry of Beta-Emitters for Intravascular Brachytherapy. United States. https://doi.org/10.2172/798524
Choi, C K. 2002.
"Monte Carol-Based Dosimetry of Beta-Emitters for Intravascular Brachytherapy". United States. https://doi.org/10.2172/798524. https://www.osti.gov/servlets/purl/798524.
@article{osti_798524,
title = {Monte Carol-Based Dosimetry of Beta-Emitters for Intravascular Brachytherapy},
author = {Choi, C K},
abstractNote = {Monte Carlo simulations for radiation dosimetry and the experimental verifications of the simulations have been developed for the treatment geometry of intravascular brachytherapy, a form of radionuclide therapy for occluded coronary disease (restenosis). Monte Carlo code, MCNP4C, has been used to calculate the radiation dose from the encapsulated array of B-emitting seeds (Sr/Y-source train). Solid water phantoms have been fabricated to measure the dose on the radiochromic films that were exposed to the beta source train for both linear and curved coronary vessel geometries. While the dose difference for the 5-degree curved vessel at the prescription point of f+2.0 mm is within the 10% guideline set by the AAPM, however, the difference increased dramatically to 16.85% for the 10-degree case which requires additional adjustment for the acceptable dosimetry planning. The experimental dose measurements agree well with the simulation results},
doi = {10.2172/798524},
url = {https://www.osti.gov/biblio/798524},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Tue Jun 25 00:00:00 EDT 2002},
month = {Tue Jun 25 00:00:00 EDT 2002}
}