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Title: Development of simulation tools for virus shell assembly. Final report

Technical Report ·
DOI:https://doi.org/10.2172/771271· OSTI ID:771271

Prof. Berger's major areas of research have been in applying computational and mathematical techniques to problems in biology, and more specifically to problems in protein folding and genomics. Significant progress has been made in the following areas relating to virus shell assembly: development has been progressing on a second-generation self-assembly simulator which provides a more versatile and physically realistic model of assembly; simulations are being developed and applied to a variety of problems in virus assembly; and collaborative efforts have continued with experimental biologists to verify and inspire the local rules theory and the simulator. The group has also worked on applications of the techniques developed here to other self-assembling structures in the material and biological sciences. Some of this work has been conducted in conjunction with Dr. Sorin Istrail when he was at Sandia National Labs.

Research Organization:
Massachusetts Institute of Technology, Cambridge, MA (US)
Sponsoring Organization:
US Department of Energy (US)
DOE Contract Number:
FG02-95ER25253
OSTI ID:
771271
Resource Relation:
Other Information: PBD: 5 Jan 2001; PBD: 5 Jan 2001
Country of Publication:
United States
Language:
English