Boron in nuclear medicine: New synthetic approaches to PET and SPECT

Technical Report · Tue Sep 01 00:00:00 EDT 1992

DOI:https://doi.org/10.2172/7199090· OSTI ID:7199090

Kabalka, G W

This annual progress report describes new methods of incorporation of radioiodine into physiologically active compounds (amphetamines), and the use of organoboranes to labeled radiopharmaceuticals with Oxygen- 15, Nitrogen-13, carbon-11 and fluorine-18. Preclinical studies are also reported on evaluation of butyothiophenones as agents acting at dopaminergic or serotonic synapses.

• Research Organization: Tennessee Univ., Knoxville, TN (United States). Dept. of Chemistry
• Sponsoring Organization: USDOE; USDOE, Washington, DC (United States)
• DOE Contract Number: FG05-86ER60434
• OSTI ID: 7199090
• Report Number(s): DOE/ER/60434-7; ON: DE92040603
• Country of Publication: United States
• Language: English

Related Subjects

62 RADIOLOGY AND NUCLEAR MEDICINE
37 INORGANIC
ORGANIC
PHYSICAL AND ANALYTICAL CHEMISTRY
AMINES
LABELLING
AMPHETAMINES
BORANES
RADIOCHEMISTRY
CARBON 11
DOPAMINE
FLUORINE 18
IODINE 123
NITROGEN 13
NUCLEAR MEDICINE
ORGANIC IODINE COMPOUNDS
OXYGEN 15
POSITRON COMPUTED TOMOGRAPHY
PROGRESS REPORT
RADIOISOTOPE GENERATORS
RADIOPHARMACEUTICALS
SEROTONIN
SINGLE PHOTON EMISSION COMPUTED TOMOGRAPHY
ANALEPTICS
AROMATICS
AUTONOMIC NERVOUS SYSTEM AGENTS
AZAARENES
AZOLES
BETA DECAY RADIOISOTOPES
BETA-PLUS DECAY RADIOISOTOPES
BORON COMPOUNDS
CARBON ISOTOPES
CARDIOTONICS
CARDIOVASCULAR AGENTS
CENTRAL NERVOUS SYSTEM AGENTS
CHEMISTRY
COMPUTERIZED TOMOGRAPHY
DIAGNOSTIC TECHNIQUES
DOCUMENT TYPES
DRUGS
ELECTRON CAPTURE RADIOISOTOPES
EMISSION COMPUTED TOMOGRAPHY
EVEN-ODD NUCLEI
FLUORINE ISOTOPES
HETEROCYCLIC COMPOUNDS
HOURS LIVING RADIOISOTOPES
HYDRIDES
HYDROGEN COMPOUNDS
HYDROXY COMPOUNDS
INDOLES
INTERMEDIATE MASS NUCLEI
IODINE ISOTOPES
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
LABELLED COMPOUNDS
LIGHT NUCLEI
MEDICINE
MINUTES LIVING RADIOISOTOPES
NANOSEC LIVING RADIOISOTOPES
NEUROREGULATORS
NITROGEN ISOTOPES
NUCLEI
ODD-EVEN NUCLEI
ODD-ODD NUCLEI
ORGANIC COMPOUNDS
ORGANIC HALOGEN COMPOUNDS
ORGANIC NITROGEN COMPOUNDS
OXYGEN ISOTOPES
PHENOLS
POLYPHENOLS
PYRROLES
RADIOISOTOPES
RADIOPROTECTIVE SUBSTANCES
SYMPATHOMIMETICS
TOMOGRAPHY
TRYPTAMINES
550601* - Medicine- Unsealed Radionuclides in Diagnostics
400201 - Chemical & Physicochemical Properties