Nonrandom mutagenesis. Progress report, March 1, 1981-February 28, 1982
The ultimate goal is the development of tools, approaches and systems which will increase our ability to detect and control mutagenesis. We have continued to develop hybrid cell lines suited to the investigation of the expression and mutagenesis of human cell surface markers. The development and characterization of the monoclonal antibody probes to identify and characterize variation in selected human cell surface antigens has continued. Human X mouse T lymphoma hybrids have proven valuable in obtaining clonal populations expressing cell surface determinants characteristic of particular differentiated cell types. We have constructed a set of human lymphocyte X mouse T lymphoma hybrids which have proven useful for the mapping of cell surface determinants to particular chromosomes.
- Research Organization:
- Univ. of Maryland, College Park, MD (United States)
- DOE Contract Number:
- AS05-78EV06024
- OSTI ID:
- 6921678
- Report Number(s):
- DOE/EV/06024-1
- Country of Publication:
- United States
- Language:
- English
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