The nucleation and growth of calcium oxalate monohydrate on self- assembled monolayers (SAMs)

Conference · Fri May 01 00:00:00 EDT 1992

OSTI ID:6630022

Campbell, A A; Tarasevich, B J; Graff, G L; Fryxell, G E; Rieke, P C

A physical chemical approach was used to study calcium oxalate monohydrate (COM) nucleation and growth on various organic interfaces. Self-assembling monolayers (SAMs), containing derivatized organic functional groups, were designed to mimic various amino acid residues present in both urine and stone matrix macromolecules. Derivatized surfaces include SAMs with terminal methyl, bromo, imidazole, and thiazolidine-carboxylic acid functional groups. Pronounced differences in COM deposition were observed for the various interfaces with the imidazole and thiazolidine surfaces having the greatest effect and the methyl and bromo groups having little or no nucleating potential.

• Research Organization: Pacific Northwest Lab., Richland, WA (United States)
• Sponsoring Organization: USDOE; USDOE, Washington, DC (United States)
• DOE Contract Number: AC06-76RL01830
• OSTI ID: 6630022
• Report Number(s): PNL-SA-20908; CONF-9205312-1; ON: DE93008989
• Resource Relation: Conference: Scanning microscopy international conference, Chicago, IL (United States), 9-14 May 1992
• Country of Publication: United States
• Language: English

Related Subjects

37 INORGANIC
ORGANIC
PHYSICAL AND ANALYTICAL CHEMISTRY
62 RADIOLOGY AND NUCLEAR MEDICINE
CALCIUM COMPOUNDS
CRYSTAL GROWTH
MINERALIZATION
OXALATES
CALCULI
NUCLEATION
VAN DER WAALS FORCES
ALKALINE EARTH METAL COMPOUNDS
CARBOXYLIC ACID SALTS
400201* - Chemical & Physicochemical Properties
550600 - Medicine