[Epithermal neutron capture therapy]

doi:10.2172/6563273

Title: [Epithermal neutron capture therapy]

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Abstract

Development of a 4 mA, 2.5 MeV Tandem Cascade Accelerator (TCA) for the production of neutrons via the [sup 7]Li(p,n)[sup 7]Be nuclear reaction is currently nearing completion at SRL. The TCA is a tandem electrostatic accelerator which uses a high current negative ion source in conjunction with a high current solid state cascade multiplier power supply to provide a compact, low cost, proton accelerator capable of supplying multi-milliampere currents at several million electron volts. The inherent simplicity and flexibility of this accelerator provide several features which are desirable for laboratory and clinical applications requiring the generation of high neutron fluxes. The beam aperture of the accelerating tube is large so that critical focusing and alignment of the beam is not required. Both the ion beam source and target are at ground potential during operation. This configuration allows different moderator geometries to be incorporated easily into the target design. A high degree of compactness is achieved by a patented SRL design which allows the power supply to be mounted directly onto the accelerating column thereby eliminating the need for an external power supply chassis. The TCA is unique in its capability to accelerate multi-milliampere ion beams to 2.5 MeV. A directmore »« less

Publication Date:: Fri Jan 01 00:00:00 EST 1993

Research Org.:: Massachusetts Inst. of Technology (MIT), Cambridge, MA (United States)

Sponsoring Org.:: USDOE; USDOE, Washington, DC (United States)

OSTI Identifier:: 6563273

Report Number(s):: DOE/ER/60874-4
ON: DE93013334

DOE Contract Number:: FG02-89ER60874

Resource Type:: Technical Report

Country of Publication:: United States

Language:: English

Subject:: 43 PARTICLE ACCELERATORS; 62 RADIOLOGY AND NUCLEAR MEDICINE; ELECTROSTATIC ACCELERATORS; DESIGN; LITHIUM 7 TARGET; NEUTRON BEAMS; NEUTRON THERAPY; PROGRESS REPORT; THERMAL NEUTRONS; WEIGHT; YIELDS; ACCELERATORS; BARYONS; BEAMS; DOCUMENT TYPES; ELEMENTARY PARTICLES; FERMIONS; HADRONS; MEDICINE; NEUTRONS; NUCLEAR MEDICINE; NUCLEON BEAMS; NUCLEONS; PARTICLE BEAMS; RADIOLOGY; RADIOTHERAPY; TARGETS; THERAPY; 430100* - Particle Accelerators- Design, Development, & Operation; 550603 - Medicine- External Radiation in Therapy- (1980-)

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                    . [Epithermal neutron capture therapy].  United States: N. p., 1993. 
        Web.  doi:10.2172/6563273.

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                    . [Epithermal neutron capture therapy].  United States.  https://doi.org/10.2172/6563273

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                    . 1993.  
        "[Epithermal neutron capture therapy]".  United States.  https://doi.org/10.2172/6563273.  https://www.osti.gov/servlets/purl/6563273.

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@article{osti_6563273,

  title        = {[Epithermal neutron capture therapy]},

  author       = {},

  abstractNote = {Development of a 4 mA, 2.5 MeV Tandem Cascade Accelerator (TCA) for the production of neutrons via the [sup 7]Li(p,n)[sup 7]Be nuclear reaction is currently nearing completion at SRL. The TCA is a tandem electrostatic accelerator which uses a high current negative ion source in conjunction with a high current solid state cascade multiplier power supply to provide a compact, low cost, proton accelerator capable of supplying multi-milliampere currents at several million electron volts. The inherent simplicity and flexibility of this accelerator provide several features which are desirable for laboratory and clinical applications requiring the generation of high neutron fluxes. The beam aperture of the accelerating tube is large so that critical focusing and alignment of the beam is not required. Both the ion beam source and target are at ground potential during operation. This configuration allows different moderator geometries to be incorporated easily into the target design. A high degree of compactness is achieved by a patented SRL design which allows the power supply to be mounted directly onto the accelerating column thereby eliminating the need for an external power supply chassis. The TCA is unique in its capability to accelerate multi-milliampere ion beams to 2.5 MeV. A direct result of the patented high current solid-state power supply developed by SRL and the use of a high current, high brightness multicusp negative ion source. The TCA requires no RF or magnetic fields which greatly reduces the system weight, power dissipation and heat load on auxiliary systems when compared with radiofrequency quadrupole (RFQ) or cyclotron-type accelerators. Delivery of current is continuous, rather than pulsed as in an RFQ, which reduces the peak thermal and mechanical stresses on the target and simplifies target design. The accelerator weighs less than 2,000 lbs., has an overall length of approximately 2.6 m, and requires approximately 25 kW of electrical power.},

  doi          = {10.2172/6563273},

  url          = {https://www.osti.gov/biblio/6563273},
  journal      = {},
number       = ,

  volume       = ,

  place        = {United States},

  year         = {Fri Jan 01 00:00:00 EST 1993},

  month        = {Fri Jan 01 00:00:00 EST 1993}

}

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