Solid state nuclear magnetic resonance studies of prion peptides and proteins
- Univ. of California, Berkeley, CA (United States)
High-resolution structural studies using x-ray diffraction and solution nuclear magnetic resonance (NMR) are not feasible for proteins of low volubility and high tendency to aggregate. Solid state NMR (SSNMR) is in principle capable of providing structural information in such systems, however to do this efficiently and accurately, further SSNMR tools must be developed This dissertation describes the development of three new methods and their application to a biological system of interest, the priori protein (PrP).
- Research Organization:
- Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States)
- Sponsoring Organization:
- USDOE Office of Science (SC); Howard Hughes Medical Institute
- DOE Contract Number:
- AC03-76SF00098
- OSTI ID:
- 6428
- Report Number(s):
- LBNL-42161; TRN: US200305%%723
- Resource Relation:
- Other Information: TH: Thesis (Ph.D.); Supercedes report DE00006428; Submitted to the Univ. of California, Dept. of Biophysics, Berkeley, CA (US); PBD: 28 Aug 1997; PBD: 28 Aug 1997
- Country of Publication:
- United States
- Language:
- English
Similar Records
Novel nuclear magnetic resonance techniques for studying biological molecules
Development of techniques in magnetic resonance and structural studies of the prion protein
Nuclear magnetic resonance studies of quadrupolar nuclei and dipolar field effects
Thesis/Dissertation
·
Thu Jun 01 00:00:00 EDT 2000
·
OSTI ID:6428
Development of techniques in magnetic resonance and structural studies of the prion protein
Thesis/Dissertation
·
Sat Jul 01 00:00:00 EDT 2000
·
OSTI ID:6428
Nuclear magnetic resonance studies of quadrupolar nuclei and dipolar field effects
Thesis/Dissertation
·
Thu Jan 01 00:00:00 EST 2004
·
OSTI ID:6428