Accelerator mass spectrometry as a bioanalytical tool for nutritional research
Abstract
Accelerator Mass Spectrometry is a mass spectrometric method of detecting long-lived radioisotopes without regard to their decay products or half-life. The technique is normally applied to geochronology, but recently has been developed for bioanalytical tracing. AMS detects isotope concentrations to parts per quadrillion, quantifying labeled biochemicals to attomole levels in milligram- sized samples. Its advantages over non-isotopeic and stable isotope labeling methods are reviewed and examples of analytical integrity, sensitivity, specificity, and applicability are provided.
- Authors:
- Publication Date:
- Research Org.:
- Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)
- Sponsoring Org.:
- USDOE, Washington, DC (United States)
- OSTI Identifier:
- 641336
- Report Number(s):
- UCRL-JC-128472; CONF-9708169-
ON: DE98053185; BR: DP0402061; CNN: W-7405-Eng-48
- DOE Contract Number:
- W-7405-ENG-48
- Resource Type:
- Conference
- Resource Relation:
- Conference: 6. international conference on nutrition and modeling, Davis, CA (United States), 11-14 Aug 1997; Other Information: PBD: 1 Sep 1997
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 55 BIOLOGY AND MEDICINE, BASIC STUDIES; CARBON 14 COMPOUNDS; MASS SPECTROSCOPY; NUTRITIONAL DEFICIENCY; LIQUID COLUMN CHROMATOGRAPHY; TRACER TECHNIQUES; RATS
Citation Formats
Vogel, J S, and Turteltaub, K W. Accelerator mass spectrometry as a bioanalytical tool for nutritional research. United States: N. p., 1997.
Web.
Vogel, J S, & Turteltaub, K W. Accelerator mass spectrometry as a bioanalytical tool for nutritional research. United States.
Vogel, J S, and Turteltaub, K W. 1997.
"Accelerator mass spectrometry as a bioanalytical tool for nutritional research". United States. https://www.osti.gov/servlets/purl/641336.
@article{osti_641336,
title = {Accelerator mass spectrometry as a bioanalytical tool for nutritional research},
author = {Vogel, J S and Turteltaub, K W},
abstractNote = {Accelerator Mass Spectrometry is a mass spectrometric method of detecting long-lived radioisotopes without regard to their decay products or half-life. The technique is normally applied to geochronology, but recently has been developed for bioanalytical tracing. AMS detects isotope concentrations to parts per quadrillion, quantifying labeled biochemicals to attomole levels in milligram- sized samples. Its advantages over non-isotopeic and stable isotope labeling methods are reviewed and examples of analytical integrity, sensitivity, specificity, and applicability are provided.},
doi = {},
url = {https://www.osti.gov/biblio/641336},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Mon Sep 01 00:00:00 EDT 1997},
month = {Mon Sep 01 00:00:00 EDT 1997}
}
Other availability
Please see Document Availability for additional information on obtaining the full-text document. Library patrons may search WorldCat to identify libraries that hold this conference proceeding.
Save to My Library
You must Sign In or Create an Account in order to save documents to your library.