Quantifying lifetime exposure to ultraviolet radiation in the epidemiology of cutaneous malignant melanoma: A pilot study

Technical Report · Thu Oct 01 00:00:00 EDT 1992

DOI:https://doi.org/10.2172/6330385· OSTI ID:6330385

Lea, C S; Selvin, S ^[1]; Buffler, P A ^[2]; Scotto, J ^[3]; Berwick, M ^[4]

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1. California Univ., Berkeley, CA (United States). Dept. of Biomedical and Environmental Health Sciences Lawrence Berkeley Lab., CA (United States)
2. California Univ., Berkeley, CA (United States). Dept. of Biomedical and Environmental Health Sciences
3. National Cancer Inst., Bethesda, MD (United States). Biostatistics Branch
4. Cancer Pre

This pilot study uses a unique method to calculate cumulative lifetime exposure to, ultraviolet radiation-b to determine if this refined method would indicate differences in lifetime cumulative UVB exposure between age and sex matched controls. Forty-four age and sex matched cases and controls demonstrated no significant difference in mean cumulative lifetime UVB exposure based on the duration and location of residence. This pilot study suggests that further analysis of the dataset should be conducted to determine if the cumulative lifetime exposure hypothesis is of primary importance regarding the association between UVB exposure and development of cutaneous malignant melanoma.

• Research Organization: Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States)
• Sponsoring Organization: USDOE; USDOE, Washington, DC (United States)
• DOE Contract Number: AC03-76SF00098
• OSTI ID: 6330385
• Report Number(s): LBL-32745; ON: DE93015274
• Country of Publication: United States
• Language: English

Related Subjects

63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
MELANOMAS
EPIDEMIOLOGY
LATITUDE EFFECT
LEVELS
LIFE SPAN
MAN
SKIN
ULTRAVIOLET RADIATION
ANIMALS
BODY
CARCINOMAS
DISEASES
ELECTROMAGNETIC RADIATION
EPITHELIOMAS
GEOGRAPHICAL VARIATIONS
MAMMALS
NEOPLASMS
ORGANS
PRIMATES
RADIATIONS
VARIATIONS
VERTEBRATES
560151* - Radiation Effects on Animals- Man