Thiophene metabolism by E. coli

Technical Report · Mon Jan 01 00:00:00 EST 1990

DOI:https://doi.org/10.2172/6296900· OSTI ID:6296900

Clark, D P

The objective of this project is to investigate the mechanism of degradation of sulfur containing heterocyclic molecules by mutants of Escherichia coli K-12. We previously isolated multiple mutants of E. coli which were selected for improved oxidation of furan and thiophene derivatives. We have focused on the thdA mutation in our subsequent research as it appears to be of central importance in thiophene oxidation. We hope that analysis of the thd gene of E. coli will lead to improvement of our thiophene metabolizing bacterial strains.

• Research Organization: Southern Illinois Univ., Carbondale, IL (USA). Dept. of Microbiology
• Sponsoring Organization: DOE/FE
• DOE Contract Number: FG22-87PC79912
• OSTI ID: 6296900
• Report Number(s): DOE/PC/79912-13; ON: DE91005924
• Country of Publication: United States
• Language: English

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