Bile salt surfactants in micellar electrokinetic capillary chromatography: Application to hydrophobic molecule separations
- Tennessee Univ., Knoxville, TN (USA). Dept. of Chemistry
- Wake Forest Univ., Winston-Salem, NC (USA). Dept. of Chemistry
- Baldwin-Wallace Coll., Berea, OH (USA). Dept. of Chemistry
Bile Salt surfactants are used in the micellar electrokinetic capillary chromatography (MECC) separation of various hydrophobic compounds. The use of methanol in the mobile phase allows the separation of previously intractable compounds including polyaromatic hydrocarbons. The effects of methanol on critical micelle concentration is investigated for sodium dodecyl sulfate (SDS) and the bile salt sodium cholate. It is determined that the unique structure of the bile salt micelle is much more tolerant to the addition of organic solvents than SDS, thereby increasing the scope of applications of MECC to include hydrophobic compounds. 30 refs., 9 figs.
- Research Organization:
- Tennessee Univ., Knoxville, TN (USA). Dept. of Chemistry
- Sponsoring Organization:
- DOE/ER
- DOE Contract Number:
- FG05-86ER13613
- OSTI ID:
- 6287336
- Report Number(s):
- DOE/ER/13613-30; ON: DE91004876
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
37 INORGANIC
ORGANIC
PHYSICAL AND ANALYTICAL CHEMISTRY
POLYCYCLIC AROMATIC HYDROCARBONS
CHROMATOGRAPHY
BILE ACIDS
ELECTROPHORESIS
EXPERIMENTAL DATA
METHANOL
MICELLAR SYSTEMS
SALTS
SURFACTANTS
ALCOHOLS
AROMATICS
CARBOXYLIC ACIDS
DATA
HYDROCARBONS
HYDROXY COMPOUNDS
INFORMATION
NUMERICAL DATA
ORGANIC ACIDS
ORGANIC COMPOUNDS
SEPARATION PROCESSES
STEROIDS
STEROLS
400105* - Separation Procedures
ORGANIC
PHYSICAL AND ANALYTICAL CHEMISTRY
POLYCYCLIC AROMATIC HYDROCARBONS
CHROMATOGRAPHY
BILE ACIDS
ELECTROPHORESIS
EXPERIMENTAL DATA
METHANOL
MICELLAR SYSTEMS
SALTS
SURFACTANTS
ALCOHOLS
AROMATICS
CARBOXYLIC ACIDS
DATA
HYDROCARBONS
HYDROXY COMPOUNDS
INFORMATION
NUMERICAL DATA
ORGANIC ACIDS
ORGANIC COMPOUNDS
SEPARATION PROCESSES
STEROIDS
STEROLS
400105* - Separation Procedures