Comparison of two lung clearance models based on the dissolution rates of oxidized depleted uranium
An in-vitro dissolution study was conducted on two respirable oxidized depleted uranium samples. The dissolution rates generated from this study were then utilized in the International Commission on Radiological Protection Task Group lung clearance model and a lung clearance model proposed by Cuddihy. Predictions from both models based on the dissolution rates of the amount of oxidized depleted uranium that would be cleared to blood from the pulmonary region following an inhalation exposure were compared. It was found that the predictions made by both models differed considerably. The difference between the predictions was attributed to the differences in the way each model perceives the clearance from the pulmonary region. 33 references, 11 figures, 9 tables.
- Research Organization:
- Los Alamos National Lab. (LANL), Los Alamos, NM (United States)
- DOE Contract Number:
- W-7405-ENG-36
- OSTI ID:
- 6237800
- Report Number(s):
- LA-10214-T; ON: DE85005190
- Resource Relation:
- Other Information: Portions are illegible in microfiche products. Original copy available until stock is exhausted. Thesis. Submitted to Texas A and M Univ., College Station
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
DEPLETED URANIUM
LUNG CLEARANCE
SOLUBILITY
MATHEMATICAL MODELS
BODY FLUIDS
COMPARATIVE EVALUATIONS
IN VITRO
INHALATION
PARTICULATES
RADIOACTIVE AEROSOLS
ACTINIDES
AEROSOLS
BIOLOGICAL MATERIALS
CLEARANCE
COLLOIDS
DISPERSIONS
ELEMENTS
EXCRETION
INTAKE
MATERIALS
METALS
PARTICLES
SOLS
URANIUM
560306* - Chemicals Metabolism & Toxicology- Man- (-1987)
560171 - Radiation Effects- Nuclide Kinetics & Toxicology- Man- (-1987)