Consortium to develop the medical uses of NMR imaging, NMR spectroscopy, and positron emission tomography. Final technical report

Pohost, G M

doi:10.2172/607522

Title: Consortium to develop the medical uses of NMR imaging, NMR spectroscopy, and positron emission tomography. Final technical report

Full Record
Other Related Research

Abstract

The goal of this work is to, perform clinically relevant studies using a new whole-body 4.1 T NMR imaging spectrometer. Initially we will develop and approach for the assessment of the severity of skeletal muscle involvement in ischemic peripheral vascular disease.

Authors:: Pohost, G M

Publication Date:: Mon Jun 01 00:00:00 EDT 1998

Research Org.:: Alabama Univ., Birmingham, AL (United States)

Sponsoring Org.:: USDOE Office of Energy Research, Washington, DC (United States)

OSTI Identifier:: 607522

Report Number(s):: DOE/ER/61386-T1
ON: DE98005340; IN: DOE/ER/GI--386-1; TRN: 98:002084

DOE Contract Number:: FG05-92ER61386

Resource Type:: Technical Report

Resource Relation:: Other Information: PBD: [1998]

Country of Publication:: United States

Language:: English

Subject:: 55 BIOLOGY AND MEDICINE, BASIC STUDIES; NMR IMAGING; SPECTROSCOPY; MUSCLES; VASCULAR DISEASES; DIAGNOSTIC TECHNIQUES; ISCHEMIA; LACTIC ACID; CARBON 13; HYDROGEN 1; GLYCOGEN

Citation Formats


                    Pohost, G M. Consortium to develop the medical uses of NMR imaging, NMR spectroscopy, and positron emission tomography. Final technical report.  United States: N. p., 1998. 
        Web.  doi:10.2172/607522.

Copy to clipboard


                    Pohost, G M. Consortium to develop the medical uses of NMR imaging, NMR spectroscopy, and positron emission tomography. Final technical report.  United States.  https://doi.org/10.2172/607522

Copy to clipboard


                    Pohost, G M. 1998.  
        "Consortium to develop the medical uses of NMR imaging, NMR spectroscopy, and positron emission tomography. Final technical report".  United States.  https://doi.org/10.2172/607522.  https://www.osti.gov/servlets/purl/607522.

Copy to clipboard


                    
@article{osti_607522,

  title        = {Consortium to develop the medical uses of NMR imaging, NMR spectroscopy, and positron emission tomography. Final technical report},

  author       = {Pohost, G M},

  abstractNote = {The goal of this work is to, perform clinically relevant studies using a new whole-body 4.1 T NMR imaging spectrometer. Initially we will develop and approach for the assessment of the severity of skeletal muscle involvement in ischemic peripheral vascular disease.},

  doi          = {10.2172/607522},

  url          = {https://www.osti.gov/biblio/607522},
  journal      = {},
number       = ,

  volume       = ,

  place        = {United States},

  year         = {Mon Jun 01 00:00:00 EDT 1998},

  month        = {Mon Jun 01 00:00:00 EDT 1998}

}

Copy to clipboard

Technical Report:

View Technical Report (0.27 MB)

https://doi.org/10.2172/607522

Save / Share:

Export Metadata

Save to My Library

Similar records in OSTI.GOV collections:

Determination of cardiac risk by dipyridamole-thallium imaging before peripheral vascular surgery

Journal Article Boucher, C; Brewster, D; Darling, R; ... - N.Engl. J. Med.; (United States)

To evaluate the severity of coronary artery disease in patients with severe peripheral vascular disease requiring surgery, preoperative dipyridamole-thallium imaging was performed in 54 stable patients with suspected coronary artery disease. Of the 54 patients, 48 had peripheral vascular surgery as scheduled without coronary angiography, of whom 8 (17 per cent) had postoperative cardiac ischemic events. The occurrence of these eight cardiac events could not have been predicted preoperatively by any clinical factors but did correlate with the presence of thallium redistribution. Eight of 16 patients with thallium redistribution had cardiac events, whereas there were no such events in 32more »« less
https://doi.org/10.1056/NEJM198502143120701
Accuracy of Tau Positron Emission Tomography as a Prognostic Marker in Preclinical and Prodromal Alzheimer Disease: A Head-to-Head Comparison Against Amyloid Positron Emission Tomography and Magnetic Resonance Imaging

Journal Article Ossenkoppele, Rik; Smith, Ruben; Mattsson-Carlgren, Niklas; ... - JAMA Neurology

Importance: Tau positron emission tomography (PET) tracers have proven useful for the differential diagnosis of dementia, but their utility for predicting cognitive change is unclear. Objective: To examine the prognostic accuracy of baseline fluorine 18 (¹⁸F)-flortaucipir and [18F]RO948 (tau) PET in individuals across the Alzheimer disease (AD) clinical spectrum and to perform a head-to-head comparison against established magnetic resonance imaging (MRI) and amyloid PET markers. Design, setting, and participants: This prognostic study collected data from 8 cohorts in South Korea, Sweden, and the US from June 1, 2014, to February 28, 2021, with a mean (SD) follow-up of 1.9 (0.8)more »« less
https://doi.org/10.1001/jamaneurol.2021.1858

Full Text Available
Preoperative evaluation of cardiac risk using dobutamine-thallium imaging in vascular surgery

Journal Article Zellner, J; Elliott, B; Robison, J; ... - Annals of Vascular Surgery; (USA)

Coronary artery disease is frequently present in patients undergoing evaluation for reconstructive peripheral vascular surgery. Dobutamine-thallium imaging has been shown to be a reliable and sensitive noninvasive method for the detection of significant coronary artery disease. Eighty-seven candidates for vascular reconstruction underwent dobutamine-thallium imaging. Forty-eight patients had an abnormal dobutamine-thallium scan. Twenty-two patients had infarct only, while 26 had reversible ischemia demonstrated on dobutamine-thallium imaging. Fourteen of 26 patients with reversible ischemia underwent cardiac catheterization and 11 showed significant coronary artery disease. Seven patients underwent preoperative coronary bypass grafting or angioplasty. There were no postoperative myocardial events in this group.more »« less
https://doi.org/10.1007/BF02009451
NMR techniques in the study of cardiovascular structure and functions

Book Osbakken, M; Haselgrove, J

The chapter titles of this book are: Introduction to NMR Techniques;Theory of NMR Probe Design;Overview of Magnetic Resonance Imaging to Study the Cardiovascular System;Vascular Anatomy and Physiology Studied with NMR Techniques;Assessment of Myocardial Ischemia and Infarction by Nuclear Magnetic Resonance Imaging;The Use of MRI in Congenital Heart Disease;Cardiomyopathies and Myocarditis Studied with NMR Techniques;Determination of Myocardial Mechanical Function with Magnetic Resonance Imaging Techniques;Determination of Flow Using NMR Techniques;The Use of Contrast Agents in Cardiac MRI;Can Cardiovascular Disease Be Effectively Evaluated with NMR Spectroscopy. NMR Studies of ATP Synthesis Reactions in the Isolated Heart;Studies of Intermediary Metabolism in the Heart bymore »« less
Smooth muscle progenitor cells from peripheral blood promote the neovascularization of endothelial colony-forming cells

Journal Article Joo, Hyung; Seo, Ha-Rim; Jeong, Hyo; ... - Biochemical and Biophysical Research Communications

Highlights: • Two distinct vascular progenitor cells are induced from adult peripheral blood. • ECFCs induce vascular structures in vitro and in vivo. • SMPCs augment the in vitro and in vivo angiogenic potential of ECFCs. • Both cell types have synergistic therapeutic potential in ischemic hindlimb model. - Abstract: Proangiogenic cell therapy using autologous progenitors is a promising strategy for treating ischemic disease. Considering that neovascularization is a harmonized cellular process that involves both endothelial cells and vascular smooth muscle cells, peripheral blood-originating endothelial colony-forming cells (ECFCs) and smooth muscle progenitor cells (SMPCs), which are similar to mature endothelialmore »« less
https://doi.org/10.1016/J.BBRC.2014.05.061

Similar Records