PCDDs (polychlorinated dibenzo-p-dioxins) and PCDFs (polychlorinated dibenzofurans) in humans

Conference · Mon Jan 01 00:00:00 EST 1990

OSTI ID:6066750

Swanson, S E ^[1]; Erickson, M D ^[2]

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1. Midwest Research Inst., Kansas City, MO (USA)
2. Argonne National Lab., IL (USA)

Numerous instances of human exposure to polychlorinated dibenzo-p- dioxins (PCDDs) and polychlorinated dibenzofurans (PCDFs) have been documented. Following the development of sufficiently specific and sensitive analytical methods during the past few years, many reports have appeared on PCDD and PCDF levels in human blood and adipose tissues. Studies have examined the PCDD and PCDF levels resulting from accidental and occupational exposures of various groups, including chemical plant workers, forestry and tannery workers, and Niet Nam veterans who had handled Agent Orange. The general background levels in the US, Federal Republic of Germany, Japan, and Sweden were also determined. The results of these studies indicate that a background level of PCDDs and PCDFs is present in the overall population. In some cases, individuals exposed to specific PCDDs or PCDFs exhibit higher levels than the general population. Isomer distribution patterns are relatively consistent and indicative of sources and metabolism. This paper reviews the available data on human PCDD and PCDF levels in exposed and general populations. 15 refs., 4 figs.

• Research Organization: Argonne National Lab., IL (USA)
• Sponsoring Organization: DOE/EH
• DOE Contract Number: W-31109-ENG-38
• OSTI ID: 6066750
• Report Number(s): CONF-9006306-1; ON: DE91006090
• Resource Relation: Conference: Electric Power Research Institute (EPRI) dioxin conference, Palo Alto, CA (USA), 11-13 Jun 1990
• Country of Publication: United States
• Language: English

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