Biological effects of 60-Hz electric fields on small and large laboratory animals
Rats and mice were exposed to 60-Hz electric fields up to 330 kV/m for durations as long as four months. No significant effects were found in the following major areas: metabolic status and growth; organ and tissue morphology; brain morphology; cardiovascular function; serum chemistry; reproduction; prenatal growth and development; teratology; bone growth; peripheral nerve function; humoral and cell-mediated immunity; susceptibility to viral infection; cell and membrane function; illness/malaise; and cytogenetics. Statistically significant effects of electric field exposures were observed in the following areas: bone fracture repair; neonatal development; neuromuscular function; endocrinology; hematology; neurochemistry; urine volume and chemistry; sympathetic nervous system; behavior. It is likely that many of the effects observed are secondary to chronic stimulation of the animal by the field. Our research efforts have shifted to an in-depth investigation of nervous system functions, with emphasis in behavior, neurochemistry, neurophysiology, and dosimetry. Current and future research in these areas will focus on: relationship of effects to field strength and duration of exposure; recovery from observed effects; fundamental understanding of observed effects; fundamental understanding of interaction of field with animal (dosimetry); and biological significance of observed effects. (ERB)
- Research Organization:
- Pacific Northwest Lab., Richland, WA (USA)
- DOE Contract Number:
- AC06-76RL01830
- OSTI ID:
- 5605734
- Report Number(s):
- PNL-SA-9406; CONF-8105140-1; ON: DE82006096
- Resource Relation:
- Conference: US/USSR scientific exchange program meeting, Kiev, USSR, 4 May 1981
- Country of Publication:
- United States
- Language:
- English
Similar Records
Biological effects of high-strength electric fields on small laboratory animals. Interim report, March 1, 1978-September 30, 1979
Studies of the teratogenic potential of exposure of rats to 6000-MHz microwave radiation. II. Postnatal psychophysiologic evaluations
Related Subjects
59 BASIC BIOLOGICAL SCIENCES
BEHAVIOR
PATHOLOGICAL CHANGES
BIOLOGICAL REPAIR
ELECTRIC FIELDS
HZ RANGE
ENDOCRINE GLANDS
HEMATOLOGY
MUSCLES
NERVOUS SYSTEM
ONTOGENESIS
BIOLOGICAL EFFECTS
BIOLOGICAL FUNCTIONS
BIOLOGICAL RECOVERY
BLOOD CHEMISTRY
BONE FRACTURES
BRAIN
CARDIOVASCULAR SYSTEM
CHROMOSOMES
CHRONIC EXPOSURE
DOSE-RESPONSE RELATIONSHIPS
DOSIMETRY
GROWTH
IMMUNITY
METABOLISM
MICE
MORPHOLOGICAL CHANGES
MORPHOLOGY
RATS
REPRODUCTION
SKELETON
TOLERANCE
ANIMALS
BODY
CENTRAL NERVOUS SYSTEM
FREQUENCY RANGE
FUNCTIONS
GLANDS
INJURIES
MAMMALS
MEDICINE
ORGANS
RECOVERY
REPAIR
RODENTS
VERTEBRATES
560400* - Other Environmental Pollutant Effects
551000 - Physiological Systems