Nuclear medicine program progress report for quarter ending December 31, 1991

Technical Report · Wed Apr 01 00:00:00 EST 1992

DOI:https://doi.org/10.2172/5402879· OSTI ID:5402879

Knapp, Jr, F F; Ambrose, K R; Callahan, A P; McPherson, D W; Mirzadeh, S; Srivastava, P C; Hasan, A; Lambert, C R; Lambert, S J; Rice, D E

This report presents information on (1) a new improved synthesis of carrier-free rhenium-188-labeled Re(V) dimercaptosuccinic acid (DMSA) complex as a potential therapeutic agent for treatment of thyroid medullary carcinoma; and (2) the synthesis and evaluation of a series of iodine-125-labeled analogues of altanserine for imaging of serotonin receptors.

• Research Organization: Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)
• Sponsoring Organization: USDOE; USDOE, Washington, DC (United States)
• DOE Contract Number: AC05-84OR21400
• OSTI ID: 5402879
• Report Number(s): ORNL/TM-12054; ON: DE92012619
• Country of Publication: United States
• Language: English

Related Subjects

62 RADIOLOGY AND NUCLEAR MEDICINE
38 RADIATION CHEMISTRY, RADIOCHEMISTRY, AND NUCLEAR CHEMISTRY
CARCINOMAS
THERAPY
ORGANIC SULFUR COMPOUNDS
LABELLING
RHENIUM COMPLEXES
CHEMICAL PREPARATION
DRUGS
IMAGES
IODINE 125
LABELLED COMPOUNDS
NUCLEAR MEDICINE
PROGRESS REPORT
REACTION INTERMEDIATES
RHENIUM 188
SEROTONIN
SUCCINIC ACID
THYROID
AMINES
AROMATICS
AUTONOMIC NERVOUS SYSTEM AGENTS
AZAARENES
AZOLES
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BODY
CARBOXYLIC ACIDS
COMPLEXES
DAYS LIVING RADIOISOTOPES
DICARBOXYLIC ACIDS
DISEASES
DOCUMENT TYPES
ELECTRON CAPTURE RADIOISOTOPES
ENDOCRINE GLANDS
GLANDS
HEAVY NUCLEI
HETEROCYCLIC COMPOUNDS
HOURS LIVING RADIOISOTOPES
HYDROXY COMPOUNDS
INDOLES
INTERMEDIATE MASS NUCLEI
INTERNAL CONVERSION RADIOISOTOPES
IODINE ISOTOPES
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
MEDICINE
MINUTES LIVING RADIOISOTOPES
NEOPLASMS
NEUROREGULATORS
NUCLEI
ODD-EVEN NUCLEI
ODD-ODD NUCLEI
ORGANIC ACIDS
ORGANIC COMPOUNDS
ORGANIC NITROGEN COMPOUNDS
ORGANS
PYRROLES
RADIOISOTOPES
RADIOPROTECTIVE SUBSTANCES
RHENIUM ISOTOPES
SYMPATHOMIMETICS
SYNTHESIS
TRANSITION ELEMENT COMPLEXES
TRYPTAMINES
550601* - Medicine- Unsealed Radionuclides in Diagnostics
550604 - Medicine- Unsealed Radionuclides in Therapy- (1980-)
400703 - Radiochemistry & Nuclear Chemistry- Radioisotope Production