Role of animal studies in low-dose extrapolation

Conference · Thu Jan 01 00:00:00 EST 1981

OSTI ID:5173951

Fry, R J.M.

Current data indicate that in the case of low-LET radiation linear, extrapolation from data obtained at high doses appears to overestimate the risk at low doses to a varying degree. In the case of high-LET radiation, extrapolation from data obtained at doses as low as 40 rad (0.4 Gy) is inappropriate and likely to result in an underestimate of the risk.

• Research Organization: Oak Ridge National Lab., TN (USA)
• DOE Contract Number: W-7405-ENG-26
• OSTI ID: 5173951
• Report Number(s): CONF-8104153-3; ON: DE82013447; TRN: 82-014130
• Resource Relation: Conference: National Council for Radiation Protection symposium on control of radiation exposures, Washington, DC, USA, 27 Apr 1981; Other Information: Portions of document are illegible
• Country of Publication: United States
• Language: English

Related Subjects

63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
LOW DOSE IRRADIATION
DOSE-RESPONSE RELATIONSHIPS
RISK ASSESSMENT
RADIATION DOSES
FORECASTING
COMPARATIVE EVALUATIONS
HEALTH HAZARDS
IN VITRO
LET
DOSES
ENERGY TRANSFER
HAZARDS
IRRADIATION
560151* - Radiation Effects on Animals- Man