Human calcium metabolism including bone resorption measured with {sup 41}Ca tracer

Conference · Thu Aug 01 00:00:00 EDT 1996

OSTI ID:390476

Freeman, S P.H.T. ^[1]; King, J C ^[2]; Vieira, N E ^[3]; Woodhouse, L R ^[2]; Yergey, A L ^[3]

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1. Lawrence Livermore National Lab., CA (United States)
2. California Univ., Berkeley, CA (United States). Dept. of Nutritional Science
3. National Inst. of Child Health and Human Development, Bethesda, MD (United States)

Accelerator mass spectrometry is so sensitive to small quantities of {sup 41}Ca that it might be used as a tracer in the study of human calcium kinetics to generate unique kinds of data. In contrast with the use of other Ca isotopic tracers, {sup 41}Ca tracer can be so administered that the tracer movements between the various body pools achieve a quasi steady state. Resorbing bone may thus be directly measured. We have tested such a protocol against a conventional stable isotope experiment with good agreement.

• Research Organization: Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)
• Sponsoring Organization: USDOE, Washington, DC (United States)
• DOE Contract Number: W-7405-ENG-48
• OSTI ID: 390476
• Report Number(s): UCRL-JC-123251; CONF-9605169-7; ON: DE96050521
• Resource Relation: Conference: 7. international accelerator mass spectrometry conference, Tucson, AZ (United States), 20-24 May 1996; Other Information: PBD: Aug 1996
• Country of Publication: United States
• Language: English

Related Subjects

55 BIOLOGY AND MEDICINE
BASIC STUDIES
ABSORPTION
REACTION KINETICS
CALCIUM 40
CALCIUM 41
ACCELERATORS
MASS SPECTROSCOPY
SKELETON
TRACER TECHNIQUES
OSTEOPOROSIS