skip to main content
OSTI.GOV title logo U.S. Department of Energy
Office of Scientific and Technical Information

Title: Enzyme catalysts for a biotechnology-based chemical industry. Quarterly progress report, April 1--June 28, 1996

Technical Report ·
DOI:https://doi.org/10.2172/383575· OSTI ID:383575

The goal of this research is to engineer enzymes to be efficient and economically attractive catalysts for the chemical industry. The author is attempted to demonstrate generally-applicable approaches to enzyme improvement as well as develop specific catalysts for potential industrial application. The paper describes the progress in two projects: (a) Random mutagenesis of pNB esterase: Improved activity and stability; and (2) Subtilisin mutants exhibiting improved ligase activity in organic solvents.

Research Organization:
California Institute of Technology (CalTech), Pasadena, CA (United States)
Sponsoring Organization:
USDOE, Washington, DC (United States)
DOE Contract Number:
FG36-93CH10578
OSTI ID:
383575
Report Number(s):
DOE/CH/10578-1; ON: DE97000516; TRN: AHC29621%%19
Resource Relation:
Other Information: PBD: 22 Jul 1996
Country of Publication:
United States
Language:
English