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Title: The impact of biology on risk assessment -- Workshop of the National Research Council`s board on radiation effects research. Meeting report

Abstract

The linear, nonthreshold extrapolation from a dose-response relationship for ionizing radiation derived at higher doses to doses for which regulatory standards are proposed is being challenged by some scientists and defended by others. It appears that the risks associated with exposures to doses of interest are below the risks that can be measured with epidemiologic studies. Therefore, many have looked to biology to provide information relevant to risk assessment. The workshop reported here, ``The Impact of biology on Risk Assessment,`` was planned to address the need for further information by bringing together scientists who have been working in key fields of biology and others who have been contemplating the issues associated specifically with this question. The goals of the workshop were to summarize and review the status of the relevant biology, to determine how the reported biologic data might influence risk assessment, and to identify subjects on which more data is needed.

Authors:
 [1];  [2];  [3];  [4];  [5];  [6];  [7];  [8]
  1. Oak Ridge National Lab., TN (United States)
  2. Univ. of California, Riverside, CA (United States)
  3. Stanford Univ., CA (United States). Dept. of Biological Sciences
  4. National Academy of Sciences, Washington, DC (United States). Board on Radiation Effects Research
  5. Harvard School of Public Health, Boston, MA (United States). Dept. of Cancer Biology
  6. Univ. of California, San Francisco, CA (United States). Dept. of Radiation Oncology
  7. Case Western Reserve Univ., Cleveland, OH (United States)
  8. Univ. of Texas Medical Branch, Galveston, TX (United States). Dept. of Radiation Therapy
Publication Date:
Research Org.:
National Academy of Sciences, Washington, DC (United States)
Sponsoring Org.:
USDOE Office of Energy Research, Washington, DC (United States)
OSTI Identifier:
319883
Report Number(s):
CONF-9707190-Summ.
ON: DE99001856; TRN: 99:003932
DOE Contract Number:  
FG02-94ER61934
Resource Type:
Conference
Resource Relation:
Conference: Workshop of the National Research Council`s Board on radiation effects research: the impact of biology on risk assessment, Washington, DC (United States), 21-22 Jul 1997; Other Information: PBD: [1997]
Country of Publication:
United States
Language:
English
Subject:
56 BIOLOGY AND MEDICINE, APPLIED STUDIES; MEETINGS; RADIATION DOSES; DOSE-RESPONSE RELATIONSHIPS; RADIATION HAZARDS; BIOLOGY; BIOLOGICAL RADIATION EFFECTS; IONIZING RADIATIONS

Citation Formats

Fry, R J.M., Grosovsky, A, Hanawalt, P C, Jostes, R F, Little, J B, Morgan, W F, Oleinick, N L, and Ullrich, R L. The impact of biology on risk assessment -- Workshop of the National Research Council`s board on radiation effects research. Meeting report. United States: N. p., 1997. Web.
Fry, R J.M., Grosovsky, A, Hanawalt, P C, Jostes, R F, Little, J B, Morgan, W F, Oleinick, N L, & Ullrich, R L. The impact of biology on risk assessment -- Workshop of the National Research Council`s board on radiation effects research. Meeting report. United States.
Fry, R J.M., Grosovsky, A, Hanawalt, P C, Jostes, R F, Little, J B, Morgan, W F, Oleinick, N L, and Ullrich, R L. 1997. "The impact of biology on risk assessment -- Workshop of the National Research Council`s board on radiation effects research. Meeting report". United States. https://www.osti.gov/servlets/purl/319883.
@article{osti_319883,
title = {The impact of biology on risk assessment -- Workshop of the National Research Council`s board on radiation effects research. Meeting report},
author = {Fry, R J.M. and Grosovsky, A and Hanawalt, P C and Jostes, R F and Little, J B and Morgan, W F and Oleinick, N L and Ullrich, R L},
abstractNote = {The linear, nonthreshold extrapolation from a dose-response relationship for ionizing radiation derived at higher doses to doses for which regulatory standards are proposed is being challenged by some scientists and defended by others. It appears that the risks associated with exposures to doses of interest are below the risks that can be measured with epidemiologic studies. Therefore, many have looked to biology to provide information relevant to risk assessment. The workshop reported here, ``The Impact of biology on Risk Assessment,`` was planned to address the need for further information by bringing together scientists who have been working in key fields of biology and others who have been contemplating the issues associated specifically with this question. The goals of the workshop were to summarize and review the status of the relevant biology, to determine how the reported biologic data might influence risk assessment, and to identify subjects on which more data is needed.},
doi = {},
url = {https://www.osti.gov/biblio/319883}, journal = {},
number = ,
volume = ,
place = {United States},
year = {Wed Dec 31 00:00:00 EST 1997},
month = {Wed Dec 31 00:00:00 EST 1997}
}

Conference:
Other availability
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