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Title: Using the TREAT reactor in support of boron neutron capture therapy (BNCT) experiments: A feasibility analysis

Abstract

The technical feasibility of using the TREAT reactor facility for boron neutron capture therapy (BNCT) research was assessed. Using one-dimensional neutronics calculations, it was shown that the TREAT core neutron spectrum can be filtered to reduce the undesired radiation (contamination) dose per desired neutron more effectively than can the core spectra from two prominent candidate reactors. Using two-dimensional calculations, it was demonstrated that a non-optimized filter replacing the TREAT thermal column can yield a fluence of desired-energy neutrons more than twice as large as the fluence believed to be required and, at the same time, have a contamination dose per desired neutron almost as low as that from any other candidate facility. The time, effort and cost required to adapt TREAT for a mission supporting BNCT research would be modest.

Authors:
;
Publication Date:
Research Org.:
Argonne National Lab. (ANL), Argonne, IL (United States)
Sponsoring Org.:
USDOE, Washington, DC (United States)
OSTI Identifier:
272551
Report Number(s):
ANL/ED-96-1
ON: DE96006286; TRN: 96:017623
DOE Contract Number:  
W-31109-ENG-38
Resource Type:
Technical Report
Resource Relation:
Other Information: PBD: Mar 1996
Country of Publication:
United States
Language:
English
Subject:
55 BIOLOGY AND MEDICINE, BASIC STUDIES; 22 NUCLEAR REACTOR TECHNOLOGY; 66 PHYSICS; TREAT REACTOR; FEASIBILITY STUDIES; BORON 10; NEUTRON REACTIONS; NEOPLASMS; NEUTRON CAPTURE THERAPY; DIAGRAMS; NUMERICAL DATA; T CODES; NEUTRONIC DAMAGE FUNCTIONS; NEUTRON SOURCE FACILITIES

Citation Formats

Grasseschi, G L, and Schaefer, R W. Using the TREAT reactor in support of boron neutron capture therapy (BNCT) experiments: A feasibility analysis. United States: N. p., 1996. Web. doi:10.2172/272551.
Grasseschi, G L, & Schaefer, R W. Using the TREAT reactor in support of boron neutron capture therapy (BNCT) experiments: A feasibility analysis. United States. https://doi.org/10.2172/272551
Grasseschi, G L, and Schaefer, R W. 1996. "Using the TREAT reactor in support of boron neutron capture therapy (BNCT) experiments: A feasibility analysis". United States. https://doi.org/10.2172/272551. https://www.osti.gov/servlets/purl/272551.
@article{osti_272551,
title = {Using the TREAT reactor in support of boron neutron capture therapy (BNCT) experiments: A feasibility analysis},
author = {Grasseschi, G L and Schaefer, R W},
abstractNote = {The technical feasibility of using the TREAT reactor facility for boron neutron capture therapy (BNCT) research was assessed. Using one-dimensional neutronics calculations, it was shown that the TREAT core neutron spectrum can be filtered to reduce the undesired radiation (contamination) dose per desired neutron more effectively than can the core spectra from two prominent candidate reactors. Using two-dimensional calculations, it was demonstrated that a non-optimized filter replacing the TREAT thermal column can yield a fluence of desired-energy neutrons more than twice as large as the fluence believed to be required and, at the same time, have a contamination dose per desired neutron almost as low as that from any other candidate facility. The time, effort and cost required to adapt TREAT for a mission supporting BNCT research would be modest.},
doi = {10.2172/272551},
url = {https://www.osti.gov/biblio/272551}, journal = {},
number = ,
volume = ,
place = {United States},
year = {Fri Mar 01 00:00:00 EST 1996},
month = {Fri Mar 01 00:00:00 EST 1996}
}