skip to main content
OSTI.GOV title logo U.S. Department of Energy
Office of Scientific and Technical Information

Title: On the processing pf piecewise-constant signals by hierarchical models with application to single ion channel currents

Conference ·
OSTI ID:224109
;  [1]; ;  [2]
  1. State Univ. of New York, Stony Brook, NY (United States). Dept. of Electrical Engineering
  2. Brookhaven National Lab., Upton, NY (United States)

A new approach for processing of piecewise-constant signals is proposed. It is based on modeling the observed data as a sum of a random signal and noise. The random signal has a Gibbs distribution, and the noise is Gaussian. A MAP criterion in derived for joint estimation of the number of signal levels and reconstruction of signal. The criterion comprises of three terms, one corresponding to the likelihood of the data and two to penalties. One penalty term penalizes for unnecessary transitions, and the other, for unnecessary levels. The method has been tested on synthesized data and applied to single ion channel recording.

Research Organization:
Brookhaven National Lab. (BNL), Upton, NY (United States)
Sponsoring Organization:
USDOE, Washington, DC (United States)
DOE Contract Number:
AC02-76CH00016
OSTI ID:
224109
Report Number(s):
BNL-62775; CONF-9605108-1; ON: DE96008216
Resource Relation:
Conference: International conference on acoustic speech and signal processing, Atlanta, GA (United States), 7 May - 10 Jun 1996; Other Information: PBD: [1996]
Country of Publication:
United States
Language:
English