A 3-D Model of Signaling and Transport Pathways in Epithelial Cells
A 3-dimensional computer model was developed to simulate the spatial and chemical evolution of calcium ions inside an array of human epithelial kidney cells. This is a prototype model, intended to develop a methodology to incorporate much more complex interactions of metabolic and other processes within many types of cells and lead to increased ability to predict cellular responses to disease as well as to chemical and biological warfare situations. Preliminary tests of the model are described.
- Research Organization:
- Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)
- Sponsoring Organization:
- US Department of Energy (US)
- DOE Contract Number:
- W-7405-ENG-48
- OSTI ID:
- 15015950
- Report Number(s):
- UCRL-TR-211112; TRN: US200509%%463
- Resource Relation:
- Other Information: PBD: 1 Apr 2005
- Country of Publication:
- United States
- Language:
- English
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