Absorbable Collagen Prosthetic Implant with Non-Absorbable Reinforcing Strands
|
patent
|
September 1966 |
Process of degrading and regenerating bone and tooth material and products
|
patent
|
October 1979 |
Composite structure vascular prostheses
|
patent
|
March 1980 |
Inductive collagen based bone repair preparations
|
patent
|
January 1986 |
Vascular grafts
|
patent
|
May 1988 |
Method for forming impregnated synthetic vascular grafts
|
patent
|
June 1989 |
Implant fixation
|
patent
|
April 1992 |
Drug delivery collagen-impregnated synthetic vascular graft
|
patent
|
March 1993 |
Stabilized FGF composition
|
patent
|
April 1993 |
Platelet derived growth factor agonists
|
patent
|
July 1994 |
Medical device with lubricious coating
|
patent
|
April 1996 |
Glycosaminoglycan-synthetic polymer conjugates
|
patent
|
April 1996 |
PDGF-B analogues
|
patent
|
April 1996 |
Fusion polypeptides and proteins
|
patent
|
October 1996 |
Peptides and compounds that bind to the IL-1 receptor
|
patent
|
March 1997 |
Peptides that bind IL-2 receptors
|
patent
|
June 1997 |
Peptides and compounds that bind selectins including endothelial leukocyte adhesion molecule 1
|
patent
|
July 1997 |
Peptides and compounds that bind to ELAM-1
|
patent
|
July 1997 |
Electrophilic polyethylene oxides for the modification of polysaccharides, polypeptides (proteins) and surfaces
|
patent
|
July 1997 |
Peptides and compounds that bind to the IL-5 receptor
|
patent
|
August 1997 |
Tubular expanded polytetrafluoroethylene implantable prostheses
|
patent
|
September 1997 |
Peptides and compounds that bind to the IL-5 receptor
|
patent
|
September 1997 |
Branched synthetic peptide conjugate
|
patent
|
October 1997 |
Fibroblast growth factor conjugates
|
patent
|
October 1997 |
Aralkyl bridged diazabicycloalkane derivatives for CNS disorders
|
patent
|
October 1997 |
Chimeric hepatocyte growth factor (HGF) ligand variants
|
patent
|
November 1997 |
Peptides and compounds that bind selectins including endothelium leukocyte adhesion molecule 1 (ELAM-1)
|
patent
|
March 1998 |
Polyvalent peptide pharmaceutical applications
|
patent
|
June 1998 |
Peptides and compounds that bind to the IL-1 receptor
|
patent
|
June 1998 |
Receptor activation with inactive hepatocyte growth factor ligands
|
patent
|
June 1998 |
Compounds and peptides that bind to the erythropoietin receptor
|
patent
|
June 1998 |
Peptides and compounds that bind selectins including endothelium leukocyte adhesion molecule 1
|
patent
|
July 1998 |
Peptides and compounds that bind to the IL-1 receptor
|
patent
|
July 1998 |
System for assaying binding to a heparin-binding growth factor receptor
|
patent
|
August 1998 |
Methods of administering peptides that bind to the erythropoietin receptor
|
patent
|
November 1998 |
Fanphiregulins: a family of heparin-binding epithelial cell growth factors
|
patent
|
November 1998 |
Compositions and therapeutic methods using morphogenic proteins and stimulatory factors
|
patent
|
December 1998 |
Peptides and compounds that bind to the IL-1 receptor
|
patent
|
January 1999 |
Medical device with biomolecule-coated surface graft matrix
|
patent
|
February 1999 |
Peptides and compounds that bind to a receptor
|
patent
|
February 1999 |
Peptides and compounds that bind to the IL-1 receptor
|
patent
|
March 1999 |
Methods of modulating tissue growth and regeneration
|
patent
|
May 1999 |
Materials and method for the immobilization of bioactive species onto biodegradable polymers
|
patent
|
June 1999 |
Multiarmed, monofunctional, polymer for coupling to molecules and surfaces
|
patent
|
August 1999 |
Process for preparing biologically compatible polymers and their use in medical devices
|
patent
|
August 1999 |
Fusion glycoproteins
|
patent
|
September 1999 |
Non-thrombogenic coating composition and methods for using same
|
patent
|
September 1999 |
Multivalent compounds for crosslinking receptors and uses thereof
|
patent
|
October 1999 |
FGF homologs
|
patent
|
November 1999 |
Interleukin-12 fusion protein
|
patent
|
November 1999 |
Hetero-polyoxime compounds and their preparation by parallel assembly
|
patent
|
December 1999 |
Circularly permuted ligands and circularly permuted chimeric molecules
|
patent
|
January 2000 |
Fusion proteins comprising multiply mutated interleukin-3 (IL-3) polypeptides and second growth factors
|
patent
|
February 2000 |
Crosslinked polymer compositions and methods for their use
|
patent
|
April 2000 |
Non-thrombogenic and anti-thrombogenic polymers
|
patent
|
August 2000 |
Drug coating with topcoat
|
patent
|
August 2000 |
Intravascular device push wire delivery system
|
patent
|
August 2000 |
Hydrogel for the therapeutic treatment of aneurysms
|
patent
|
September 2000 |
Medical device coated with interpenetrating network of hydrogel polymers
|
patent
|
September 2000 |
Multivalent ligands which modulate angiogenesis
|
patent
|
September 2000 |
Vasoocclusive coil
|
patent
|
October 2000 |
Three dimensional spherical micro-coils manufactured from radiopaque nickel-titanium microstrand
|
patent
|
December 2000 |
Intravascular flow modifier and reinforcement device
|
patent
|
December 2000 |
Method and apparatus for occlusion and reinforcement of aneurysms
|
patent
|
January 2001 |
N-terminal modifications of RANTES and methods of use
|
patent
|
January 2001 |
Three dimensional, low friction vasoocclusive coil, and method of manufacture
|
patent
|
January 2001 |
Homogeneous polyoxime compositions and their preparation by parallel assembly
|
patent
|
January 2001 |
Chimeric proteins
|
patent
|
January 2001 |
Peptide compounds useful for modulating FGF receptor activity
|
patent
|
April 2001 |
Polyoxime compounds and their preparation
|
patent
|
April 2001 |
Shape memory segmented detachable coil
|
patent
|
April 2001 |
Stents with hybrid coating for medical devices
|
patent
|
May 2001 |
Compositions for coating microcapsules and other surfaces
|
patent
|
May 2001 |
Multivalent ligands which modulate angiogenesis
|
patent
|
May 2001 |
Absorbable brachytherapy and chemotherapy delivery devices and methods
|
patent
|
June 2001 |
Peptides and compounds that bind to a receptor
|
patent
|
June 2001 |
Method for making biocompatible medical article
|
patent
|
July 2001 |
Implantable medical device
|
patent
|
August 2001 |
Composition and method for regulating the adhesion of cells and biomolecules to hydrophobic surfaces
|
patent
|
September 2001 |
Human basic fibroblast growth factor analog
|
patent
|
September 2001 |
Vasoocclusive coil
|
patent
|
October 2001 |
ePTFE small caliber vascular grafts with significant patency enhancement via a surface coating which contains covalently bonded heparin
|
patent
|
October 2001 |
Universal biocompatible coating platform for medical devices
|
patent
|
October 2001 |
Ligand-binding, dimerized polypeptide fusions
|
patent
|
November 2001 |
Solid phase native chemical ligation of unprotected or n-terminal cysteine protected peptides in aqueous solution
|
patent
|
December 2001 |
Amphipathic coating for modulating cellular adhesion composition and methods
|
patent
|
January 2002 |
Platelet-derived growth factor analogues
|
patent
|
February 2002 |
Expanded polytetrafluoroethylene vascular graft with coating
|
patent
|
April 2002 |
Arrangement for spectral interferometric optical tomography and surface profile measurement
|
patent
|
April 2002 |
Variable stiffness coil for vasoocclusive devices
|
patent
|
May 2002 |
Medical devices comprising ionically and non-ionically crosslinked polymer hydrogels having improved mechanical properties
|
patent
|
May 2002 |
Non-thrombogenic and anti-thrombogenic polymers
|
patent
|
June 2002 |
Crosslinkable macromers
|
patent
|
June 2002 |
Intravascular flow modifier and reinforcement device
|
patent
|
July 2002 |
Matrix-free osteogenic devices, implants and methods of use thereof
|
patent
|
July 2002 |
Lipid matrix-assisted chemical ligation and synthesis of membrane polypeptides
|
patent
|
September 2002 |
Compositions and systems for forming crosslinked biomaterials and associated methods of preparation and use
|
patent
|
October 2002 |
Medical device comprising glycosaminoglycan-antithrombin III/heparin cofactor II conjugates
|
patent
|
December 2002 |
Implant coating for control of tissue/implant interactions
|
patent
|
December 2002 |
Methods for forming regional tissue adherent barriers and drug delivery systems
|
patent
|
February 2003 |
Cross-linked polymer compositions and methods for their use
|
patent
|
March 2003 |
Synthetic peptides having FGF receptor affinity
|
patent
|
April 2003 |
Shape memory segmented detachable coil
|
patent
|
April 2003 |
Implantable device having substances impregnated therein and a method of impregnating the same
|
patent
|
July 2003 |
Nucleic acid coating compositions and methods
|
patent
|
July 2003 |
Vasoocclusive device for treatment of aneurysms
|
patent
|
September 2003 |
Silyl and Heparin compositions
|
patent
|
October 2003 |
Three dimensional, low friction vasoocclusive coil, and method of manufacture
|
patent
|
October 2003 |
Variable stiffness coil for vasoocclusive devices
|
patent
|
December 2003 |
Intravascular flow modifier and reinforcement device
|
patent
|
December 2003 |
In situ polymerizable hydrogels
|
patent
|
November 2004 |
Calcium phosphate bone graft material, process for making same and osteoimplant fabricated from same
|
patent
|
January 2005 |
Composite shaped bodies and methods for their production and use
|
patent
|
March 2005 |
Product display rack
|
patent
|
March 2005 |
Bioactive coating composition and methods
|
patent
|
July 2005 |
Porous β-tricalcium phosphate granules for regeneration of bone tissue
|
patent
|
September 2005 |
Biodegradable elastomer and method of preparing same
|
patent
|
January 2006 |
Methods for forming regional tissue adherent barriers and drug delivery systems
|
patent
|
April 2006 |
Osteogenic devices and methods of use thereof for repair of endochondral bone and osteochondral defects
|
patent
|
May 2006 |
Synthetic heparin-binding growth factor analogs
|
patent
|
January 2007 |
Compositions and methods for treating diverticular disease
|
patent
|
July 2007 |
Polypeptide variants with increased heparin-binding capacity
|
patent
|
August 2007 |
Growth factor analogs
|
patent
|
August 2008 |
Cross-linked heparin coatings and methods
|
patent
|
December 2008 |
Positive modulator of bone morphogenic protein-2
|
patent
|
January 2009 |
Heterodimeric chain synthetic heparin-binding growth factor analogs
|
patent
|
May 2009 |
Dual chain synthetic heparin-binding growth factor analogs
|
patent
|
October 2009 |
Formulations and methods for delivery of growth factor analogs
|
patent
|
March 2010 |
Synthetic heparin-binding factor analogs
|
patent
|
April 2010 |
Laminin-derived multi-domain peptides
|
patent
|
October 2010 |
Composition comprising BMP-2 amplifier/co-activator for enhancement of osteogenesis
|
patent
|
July 2011 |
Single branch heparin-binding growth factor analogs
|
patent
|
January 2012 |
Dual chain synthetic heparin-binding growth factor analogs
|
patent
|
April 2012 |
FGF growth factor analogs
|
patent
|
July 2012 |
Improved Osteogenic Devices and Methods of Use Therof for Repair of Endochondral Bone and Osteochondral Defects
|
patent-application
|
August 2001 |
Non-thrombogenic coating composition and methods for using same
|
patent-application
|
August 2002 |
Nucleic acid coating compositions and methods
|
patent-application
|
October 2002 |
Osteogenic devices
|
patent-application
|
December 2003 |
Synthetic heparin-binding growth factor analogs
|
patent-application
|
February 2004 |
Devices and methods for mixing and extruding medically useful compositions
|
patent-application
|
April 2004 |
Synthetic heparin-binding factor analogs
|
patent-application
|
May 2004 |
Bioactive medical films
|
patent-application
|
August 2004 |
Positive modulator of bone morphogenic protein-2
|
patent-application
|
September 2005 |
Macroporous, resorbable and injectible calcium phosphate-based cements (MCPC) for bone repair, augmentation, regeneration, and osteoporosis treatment
|
patent-application
|
September 2005 |
Dual chain synthetic heparin-binding growth factor analogs
|
patent-application
|
October 2005 |
Bioactive peptide coatings
|
patent-application
|
February 2006 |
FGF growth factor analogs
|
patent-application
|
September 2006 |
Formulations and methods for delivery of growth factor analogs
|
patent-application
|
September 2006 |
Composition and Method for Delivery of BMP-2 Amplifier/Co-Activator for Enhancement of Osteogenesis
|
patent-application
|
March 2008 |
Coating Device and Method for Coating Medical Device with Bioactive Peptide
|
patent-application
|
July 2008 |
Positive Modulator of Bone Morphogenic Protein-2
|
patent-application
|
July 2008 |
Single branch heparin-binding growth factor analogs
|
patent-application
|
September 2008 |
Cysteine-branched heparin-binding growth factor analogs
|
patent-application
|
April 2009 |
Growth Factor Analogs
|
patent-application
|
June 2009 |
Dual Chain Synthetic Heparin-Binding Growth Factor Analogs
|
patent-application
|
October 2010 |
Single Branch Heparin-Binding Growth Factor Analogs
|
patent-application
|
November 2010 |
Composition and Method for Delivery of BMP-2 Amplifier/Co-Activator for Enhancement of Osteogenesis
|
patent-application
|
December 2011 |
Dual Chain Synthetic Heparin-Binding Growth Factor Analogs
|
patent-application
|
December 2012 |
Keratinocyte Growth Factor: A Fibroblast Growth Factor Family Member with Unusual Target Cell Specificity
|
journal
|
December 1991 |
Heparin-Binding EGF-like Growth Factor: Characterization of Rat and Mouse cDNA Clones, Protein Domain Conservation across Species, and Transcript Expression in Tissues
|
journal
|
January 1993 |
Constitutively Active BMP Type I Receptors Transduce BMP-2 Signals without the Ligand in C2C12 Myoblasts
|
journal
|
September 1997 |
A Recombinant Human TGF-β1 Fusion Protein with Collagen-Binding Domain Promotes Migration, Growth, and Differentiation of Bone Marrow Mesenchymal Cells
|
journal
|
August 1999 |
Smads as transcriptional co-modulators
|
journal
|
April 2000 |
Semirational design of a potent, artificial agonist of fibroblast growth factor receptors
- Ballinger, Marcus D.; Shyamala, Venkatakrishna; Forrest, Louise D.
-
Nature Biotechnology, Vol. 17, Issue 12, p. 1199-1204
https://doi.org/10.1038/70746
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journal
|
December 1999 |
Biosynthesis of human fibroblast growth factor-5.
|
journal
|
April 1991 |
Identification of a peptide blocking vascular endothelial growth factor (VEGF)-mediated angiogenesis
|
journal
|
April 2000 |
Overlapping Expression and Redundant Activation of Mesenchymal Fibroblast Growth Factor (FGF) Receptors by Alternatively Spliced FGF-8 Ligands
|
journal
|
February 1997 |
Go hunting in sequence databases but watch out for the traps
|
journal
|
October 1996 |
Powers and Pitfalls in Sequence Analysis: The 70% Hurdle
|
journal
|
April 2000 |
Identification of a cyclic peptide inhibitor of platelet-derived growth factor-BB receptor-binding and mitogen-induced DNA synthesis in human fibroblasts
|
journal
|
August 1997 |
Evolutionary grouping of the transforming growth factor-β superfamily
|
journal
|
April 1992 |
Trans-repressor activity of nuclear glycosaminoglycans on Fos and Jun/AP-1 oncoprotein-mediated transcription
|
journal
|
January 1992 |
Mitogenic properties of a new endothelial cell growth factor related to pleiotrophin
|
journal
|
October 1991 |
Synthesis of Native Proteins by Chemical Ligation
|
journal
|
June 2000 |
A Functional Fibroblast Growth Factor-1 Immunoglobulin Fusion Protein
|
journal
|
June 1998 |
FGF Signaling Controls Somite Boundary Position and Regulates Segmentation Clock Control of Spatiotemporal Hox Gene Activation
|
journal
|
July 2001 |
Tandem Ligation of Multipartite Peptides with Cell-Permeable Activity
|
journal
|
January 2003 |
Multiple peptide synthesis
|
journal
|
April 1995 |
Structure and Sequence of HumanFGF8
|
journal
|
July 1996 |
Bone Morphogenetic Protein Receptor Complexes on the Surface of Live Cells: A New Oligomerization Mode for Serine/Threonine Kinase Receptors
|
journal
|
March 2000 |
Identification and characterization of a novel member of the fibroblast growth factor family
|
journal
|
May 1998 |
Structural and functional characterization of full-length heparin-binding growth associated molecule.
|
journal
|
January 1992 |
Stimulatory Effects of Basic Fibroblast Growth Factor and Bone Morphogenetic Protein-2 on Osteogenic Differentiation of Rat Bone Marrow-Derived Mesenchymal Stem Cells
|
journal
|
October 1997 |
Designing Biomaterials to Direct Biological Responses
|
journal
|
June 1999 |
MADR1, a MAD-Related Protein That Functions in BMP2 Signaling Pathways
|
journal
|
May 1996 |
Tumor necrosis factor receptor family member RANK mediates osteoclast differentiation and activation induced by osteoprotegerin ligand
|
journal
|
March 1999 |
FGF-18, a Novel Member of the Fibroblast Growth Factor Family, Stimulates Hepatic and Intestinal Proliferation
|
journal
|
October 1998 |
Amino-terminal sequences of a novel heparin-binding protein from human, bovine, rat, and chick brain: High interspecies homology
|
journal
|
April 1990 |
Specific Activation of the p38 Mitogen-activated Protein Kinase Signaling Pathway and Induction of Neurite Outgrowth in PC12 Cells by Bone Morphogenetic Protein-2
|
journal
|
September 1999 |
The NH2-terminal region of the active domain of sonic hedgehog is necessary for its signal transduction
|
journal
|
March 1999 |
Cloning of a Novel Type II Serine/Threonine Kinase Receptor through Interaction with the Type I Transforming Growth Factor-β Receptor
|
journal
|
March 1995 |
Fibroblasts expressing Sonic hedgehog induce osteoblast differentiation and ectopic bone formation
|
journal
|
March 1997 |
BMP-2 antagonists emerge from alterations in the low-affinity binding epitope for receptor BMPR-II
|
journal
|
July 2000 |
BMP signaling components are expressed in human fracture callus
|
journal
|
September 2003 |
Design and Chemical Synthesis of a Homogeneous Polymer-Modified Erythropoiesis Protein
|
journal
|
February 2003 |
Cloning and Characterization of a cDNA Encoding a Novel Fibroblast Growth Factor Preferentially Expressed in Human Heart
|
journal
|
February 1999 |
Characterization of heparin-binding growth-associated factor receptor on NIH 3T3 cells
|
journal
|
January 1992 |
Silyl-heparin bonding improves the patency and in vivo thromboresistance of carbon-coated polytetrafluoroethylene vascular grafts
|
journal
|
May 2004 |
Multidomain Synthetic Peptide B2A2 Synergistically Enhances BMP-2 In Vitro
|
journal
|
November 2004 |
A synthetic, bioactive PDGF mimetic with binding to both α-PDGF and β-PDGF receptors
|
journal
|
January 2007 |
Augmentation of osseous phenotypes in vivo with a synthetic peptide
|
journal
|
January 2007 |
Preferential antagonism of the interactions of the integrin αIIbβ3 with immobilized glycoprotein ligands by snake-venom RGD (Arg-Gly-Asp) proteins. Evidence supporting a functional role for the amino acid residues flanking the tripeptide RGD in determining the inhibitory properties of snake-venom RGD proteins
|
journal
|
December 1994 |
Human keratinocyte growth factor activity on proliferation and differentiation of human keratinocytes: Differentiation response distinguishes KGF from EGF family
|
journal
|
August 1990 |
Appearance of heparin-binding EGF-like growth factor in wound fluid as a response to injury.
|
journal
|
May 1993 |
[1] Concept and early development of solid-phase peptide synthesis
|
book
|
January 1997 |
Structure and Expression of a Novel Member, FGF-16, of the Fibroblast Growth Factor Family
|
journal
|
February 1998 |
Induction of Osteogenic Differentiation by Hedgehog Proteins
|
journal
|
August 1997 |
Identification of a novel fibroblast growth factor, FGF-22, preferentially expressed in the inner root sheath of the hair follicle
|
journal
|
February 2001 |
Identification of a novel FGF, FGF-21, preferentially expressed in the liver
|
journal
|
June 2000 |
The Mode of Bone Morphogenetic Protein (BMP) Receptor Oligomerization Determines Different BMP-2 Signaling Pathways
|
journal
|
November 2001 |
Identification of a Human Type II Receptor for Bone Morphogenetic Protein-4 That Forms Differential Heteromeric Complexes with Bone Morphogenetic Protein Type I Receptors
|
journal
|
September 1995 |
Peptide Synthesis via Fragment Condensation
|
book
|
November 1994 |
Structure and Expression of the mRNA Encoding a Novel Fibroblast Growth Factor, FGF-18
|
journal
|
July 1998 |
FGF-20, a Novel Neurotrophic Factor, Preferentially Expressed in the Substantia Nigra Pars Compacta of Rat Brain
|
journal
|
October 2000 |
Endothelial Apoptosis as the Primary Lesion Initiating Intestinal Radiation Damage in Mice
|
journal
|
July 2001 |
Role of heparan sulfate in fibroblast growth factor signalling: a structural view
|
journal
|
September 2001 |
Polymeric system for dual growth factor delivery
|
journal
|
November 2001 |
αvβ3 Integrin Mediates the Cell-adhesive Capacity and Biological Activity of Basic Fibroblast Growth Factor (FGF-2) in Cultured Endothelial Cells
|
journal
|
December 1997 |
Activation of osteo-progenitor cells by a novel synthetic peptide derived from the bone morphogenetic protein-2 knuckle epitope
|
journal
|
September 2003 |
Prolonged ectopic calcification induced by BMP-2-derived synthetic peptide
|
journal
|
January 2004 |
Enhanced osteogenic promotion around dental implants with synthetic binding motif mimicking bone morphogenetic protein (BMP)-2
|
journal
|
January 2006 |
From genes to protein structure and function: novel applications of computational approaches in the genomic era
|
journal
|
January 2000 |
The challenges of genome sequence annotation or “The devil is in the details”
|
journal
|
November 1997 |
Alginate hydrogel linked with synthetic oligopeptide derived from BMP-2 allows ectopic osteoinduction in vivo
|
journal
|
June 2000 |
Directly Linked Soluble il-6 Receptor–Il-6 Fusion Protein Induces Astrocyte Differentiation from Neuroepithelial Cells via Activation of Stat3
|
journal
|
March 2001 |
Involvement of bone morphogenic protein‐2 (BMP‐2) in the pathological ossification process of the spinal ligament
|
journal
|
October 2001 |
A Novel Isoform of Human Fibroblast Growth Factor 8 Is Induced by Androgens and Associated with Progression of Esophageal Carcinoma
|
journal
|
January 2001 |
Design of Peptides with High Affinities for Heparin and Endothelial Cell Proteoglycans
|
journal
|
March 2000 |
Basic fibroblast growth factor and bone induction in rats
|
journal
|
January 1993 |
Genomic structure, mapping, activity and expression of fibroblast growth factor 17
|
journal
|
May 1999 |
Identification of a Novel Fibroblast Growth Factor, FGF-23, Preferentially Expressed in the Ventrolateral Thalamic Nucleus of the Brain
|
journal
|
October 2000 |
RGD motif enhances immunogenicity and adjuvanicity of peptide antigens following intranasal immunization
|
journal
|
December 2003 |
Engineering of an FGF–proteoglycan fusion protein with heparin-independent, mitogenic activity
|
journal
|
June 2000 |
Sonic hedgehog is involved in osteoblast differentiation by cooperating with BMP-2
|
journal
|
October 2002 |
Local Delivery of Basic Fibroblast Growth Factor (bFGF) Using Adsorbed Silyl-heparin, Benzyl-bis(dimethylsilylmethyl)oxycarbamoyl-heparin
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journal
|
September 2002 |
The human FGF-5 oncogene encodes a novel protein related to fibroblast growth factors.
|
journal
|
August 1988 |
The Spemann Organizer Signal noggin Binds and Inactivates Bone Morphogenetic Protein 4
|
journal
|
August 1996 |