Dynamic Conformations of Nucleosome Arrays in Solution from Small-Angle X-ray Scattering
- George Washington Univ., Washington, DC (United States)
We set out to determine quantitative information regarding the dynamic conformation of nucleosome arrays in solution using experimental SAXS. Toward this end, we developed a CG simulation algorithm for dsDNA which rapidly generates ensembles of structures through Metropolis MC sampling of a Markov chain.
- Research Organization:
- Brookhaven National Lab. (BNL), Upton, NY (United States)
- Sponsoring Organization:
- USDOE Office of Science (SC), Biological and Environmental Research (BER)
- DOE Contract Number:
- SC00112704
- OSTI ID:
- 1338475
- Report Number(s):
- BNL-113354-2016-TH
- Country of Publication:
- United States
- Language:
- English
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