Transcranial stimulation over the left inferior frontal gyrus increases false alarms in an associative memory task in older adults

Leach, Ryan C.; McCurdy, Matthew P.; Trumbo, Michael C.; Matzen, Laura E.; Leshikar, Eric D.

doi:10.1097/01.hxr.0000491108.83234.85

Title: Transcranial stimulation over the left inferior frontal gyrus increases false alarms in an associative memory task in older adults

Journal Article · Fri Jul 15 00:00:00 EDT 2016 · Healthy Aging Research

DOI:https://doi.org/10.1097/01.hxr.0000491108.83234.85· OSTI ID:1338318

Leach, Ryan C. ^[1]; McCurdy, Matthew P. ^[1]; Trumbo, Michael C. ^[2]; Matzen, Laura E. ^[3]; Leshikar, Eric D. ^[1]

Univ. of Illinois, Chicago, IL (United States)
Univ. of New Mexico, Albuquerque, NM (United States)
Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

Here, transcranial direct current stimulation (tDCS) is a potent ial tool for alleviating various forms of cognitive decline, including memory loss, in older adults. However, past effects of tDCS on cognitive ability have been mixed. One important potential moderator of tDCS effects is the baseline level of cognitive performance. We tested the effects of tDCS on face-name associative memory in older adults, who suffer from performance deficits in this task relative to younger adults. Stimulation was applied to the left inferior prefrontal cortex during encoding of face-name pairs, and memory was assessed with both a recognition and recall task. As a result, face–name memory performance was decreased with the use of tDCS. This result was driven by increased false alarms when recognizing rearranged face–name pairs.

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Research Organization:: Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

Sponsoring Organization:: USDOE National Nuclear Security Administration (NNSA)

Grant/Contract Number:: AC04-94AL85000

OSTI ID:: 1338318

Report Number(s):: SAND-2016-8019J; 646704

Journal Information:: Healthy Aging Research, Vol. 5; ISSN 2261-7434

Country of Publication:: United States

Language:: English

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Systematic Review and Network Meta-Analysis of Anodal tDCS Effects on Verbal Episodic Memory: Modeling Heterogeneity of Stimulation Locations Bartl, Gergely Janos; Blackshaw, Emily; Crossman, Margot Zeitschrift für Psychologie, Vol. 228, Issue 1 https://doi.org/10.1027/2151-2604/a000396	journal	March 2020
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