Rapid and highly fieldable viral diagnostic

McKnight, Timothy E.

Title: Rapid and highly fieldable viral diagnostic

Patent · Tue Dec 20 00:00:00 EST 2016

OSTI ID:1336928

McKnight, Timothy E.

The present invention relates to a rapid, highly fieldable, nearly reagentless diagnostic to identify active RNA viral replication in a live, infected cells, and more particularly in leukocytes and tissue samples (including biopsies and nasal swabs) using an array of a plurality of vertically-aligned nanostructures that impale the cells and introduce a DNA reporter construct that is expressed and amplified in the presence of active viral replication.

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Research Organization:: Oak Ridge National Laboratory (ORNL), Oak Ridge, TN (United States)

Sponsoring Organization:: USDOE

DOE Contract Number:: AC05-00OR22725

Assignee:: UT-Battelle, LLC (Oak Ridge, TN)

Patent Number(s):: 9,523,132

Application Number:: 14/212,718

OSTI ID:: 1336928

Resource Relation:: Patent File Date: 2014 Mar 14

Country of Publication:: United States

Language:: English

References (29)

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