Energy Triplets for Writing Epigenetic Marks: Insights from QM/MM Free-Energy Simulations of Protein Lysine Methyltransferases
|
journal
|
November 2009 |
QM/MM MD and Free Energy Simulations of G9a-Like Protein (GLP) and Its Mutants: Understanding the Factors that Determine the Product Specificity
|
journal
|
May 2012 |
QM/MM Free Energy Simulations of Salicylic Acid Methyltransferase: Effects of Stabilization of TS-like Structures on Substrate Specificity
|
journal
|
January 2011 |
Mechanism of histone methylation catalyzed by protein lysine methyltransferase SET7/9 and origin of product specificity
|
journal
|
May 2007 |
Arginine methylation regulates the p53 response
|
journal
|
November 2008 |
Active site dynamics in protein molecules: A stochastic boundary molecular-dynamics approach
|
journal
|
May 1985 |
Crystal Structure of the Plant Epigenetic Protein Arginine Methyltransferase 10
|
journal
|
November 2011 |
Type II protein arginine methyltransferase 5 (PRMT5) is required for circadian period determination in Arabidopsis thaliana
|
journal
|
November 2010 |
Arginine methylation mediated by the Arabidopsis homolog of PRMT5 is essential for proper pre-mRNA splicing
|
journal
|
October 2010 |
A combined quantum mechanical and molecular mechanical potential for molecular dynamics simulations
|
journal
|
July 1990 |
Understanding Energetic Origins of Product Specificity of SET8 from QM/MM Free Energy Simulations: What Causes the Stop of Methyl Addition during Histone Lysine Methylation?
|
journal
|
March 2010 |
CHARMM: A program for macromolecular energy, minimization, and dynamics calculations
|
journal
|
July 1983 |
THE weighted histogram analysis method for free-energy calculations on biomolecules. I. The method
|
journal
|
October 1992 |
The Sm-Protein Methyltransferase, Dart5, Is Essential for Germ-Cell Specification and Maintenance
|
journal
|
June 2006 |
A methyl transferase links the circadian clock to the regulation of alternative splicing
|
journal
|
October 2010 |
SKB1-mediated symmetric dimethylation of histone H4R3 controls flowering time in Arabidopsis
|
journal
|
March 2007 |
Functional involvement of Tudor and dPRMT5 in the piRNA processing pathway in Drosophila germlines
|
journal
|
December 2009 |
Methylation of histone H4 at arginine 3 occurs in vivo and is mediated by the nuclear receptor coactivator PRMT1
|
journal
|
June 2001 |
Comparison of simple potential functions for simulating liquid water
|
journal
|
July 1983 |
Self-consistent-charge density-functional tight-binding method for simulations of complex materials properties
|
journal
|
September 1998 |
Substrate Specificity, Processivity, and Kinetic Mechanism of Protein Arginine Methyltransferase 5
|
journal
|
July 2013 |
Crystal Structure of Arginine Methyltransferase 6 from Trypanosoma brucei
|
journal
|
February 2014 |
Histone arginine methylation and its dynamic regulation
|
journal
|
January 2006 |
Monte Carlo free energy estimates using non-Boltzmann sampling: Application to the sub-critical Lennard-Jones fluid
|
journal
|
October 1974 |
All-Atom Empirical Potential for Molecular Modeling and Dynamics Studies of Proteins †
|
journal
|
April 1998 |
An Allosteric Inhibitor of Protein Arginine Methyltransferase 3
|
journal
|
August 2012 |
Theoretical Insights into Catalytic Mechanism of Protein Arginine Methyltransferase 1
|
journal
|
August 2013 |
Histone arginine methylation
|
journal
|
November 2010 |
PRMT5-mediated methylation of histone H4R3 recruits DNMT3A, coupling histone and DNA methylation in gene silencing
|
journal
|
February 2009 |
Structural and Sequence Motifs of Protein (Histone) Methylation Enzymes
|
journal
|
June 2005 |
Crystal structure of the human PRMT5:MEP50 complex
|
journal
|
October 2012 |
Caenorhabditis elegans Protein Arginine Methyltransferase PRMT-5 Negatively Regulates DNA Damage-Induced Apoptosis
|
journal
|
June 2009 |
Protein Arginine Methylation in Mammals: Who, What, and Why
|
journal
|
January 2009 |
Non-histone protein methylation as a regulator of cellular signalling and function
|
journal
|
December 2014 |
Methylation of Histone H4 at Arginine 3 Facilitating Transcriptional Activation by Nuclear Hormone Receptor
|
journal
|
May 2001 |
Structural Determinants for the Strict Monomethylation Activity by Trypanosoma brucei Protein Arginine Methyltransferase 7
|
journal
|
May 2014 |
A QM/MM Implementation of the Self-Consistent Charge Density Functional Tight Binding (SCC-DFTB) Method
|
journal
|
January 2001 |
Protein Arginine Methyltransferase 5 Catalyzes Substrate Dimethylation in a Distributive Fashion
|
journal
|
December 2014 |
Quantum Mechanical/Molecular Mechanical Study of Catalytic Mechanism and Role of Key Residues in Methylation Reactions Catalyzed by Dimethylxanthine Methyltransferase in Caffeine Biosynthesis
|
journal
|
January 2014 |
Structural insights into protein arginine symmetric dimethylation by PRMT5
|
journal
|
December 2011 |
QM/MM MD and free energy simulations of the methylation reactions catalyzed by protein arginine methyltransferase PRMT3
|
journal
|
July 2013 |
Computational Study of Methionine Methylation Process Catalyzed by SETD3
|
journal
|
April 2022 |
Methylation of Sm proteins by a complex containing PRMT5 and the putative U snRNP assembly factor pICln
|
journal
|
December 2001 |
Structure of the Predominant Protein Arginine Methyltransferase PRMT1 and Analysis of Its Binding to Substrate Peptides
|
journal
|
May 2003 |
Inhibition mechanism of the chloride channel TMEM16A by the pore blocker 1PBC
|
journal
|
May 2022 |