Nucleic acids encoding mosaic HIV-1 gag proteins

Korber, Bette T.; Perkins, Simon; Bhattacharya, Tanmoy; Fischer, William M.; Theiler, James; Letvin, Norman; Haynes, Barton F.; Hahn, Beatrice H.; Yusim, Karina; Kuiken, Carla

Title: Nucleic acids encoding mosaic HIV-1 gag proteins

Patent · Tue Nov 15 00:00:00 EST 2016

OSTI ID:1332283

Korber, Bette T.; Perkins, Simon; Bhattacharya, Tanmoy; Fischer, William M.; Theiler, James; Letvin, Norman; Haynes, Barton F.; Hahn, Beatrice H.; Yusim, Karina; Kuiken, Carla

The disclosure generally relates to an immunogenic composition (e.g., a vaccine) and, in particular, to a polyvalent immunogenic composition, such as a polyvalent HIV vaccine, and to methods of using same.

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Research Organization:: Los Alamos National Laboratory (LANL), Los Alamos, NM (United States)

Sponsoring Organization:: USDOE

DOE Contract Number:: AC52-06NA25396

Assignee:: LOS ALAMOS NATIONAL SECURITY, LLC (Los Alamos, MX

Patent Number(s):: 9,492,532

Application Number:: 14/689,957

OSTI ID:: 1332283

Resource Relation:: Patent File Date: 2015 Apr 17

Country of Publication:: United States

Language:: English

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Mosaic clade M human immunodeficiency virus type 1 (HIV-1) envelope immunogens Korber, Bette T.; Fischer, William M.; Liao, Hua-Xin https://doi.org/https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/7951377 US Patent Document 7,951,377	patent	May 2011
Immunogenic compositions comprising human immunodeficiency virus (HIV) mosaic Nef proteins Korber, Bette T.; Perkins, Simon; Bhattacharya, Tanmoy https://doi.org/https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/8119140 US Patent Document 8,119,140	patent	February 2012
Nucleic acids encoding mosaic clade M human immunodeficiency virus type 1 (HIV-1) envelope immunogens Korber, Bette T.; Fischer, William M.; Liao, Hua-Xin https://doi.org/https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/9011873 US Patent Document 9,011,873	patent	April 2015
Human immunodeficiency virus type 1 clade M mosaic gag polypeptides Korber, Bette T.; Perkins, Simon; Bhattacharya, Tanmoy https://doi.org/https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/9011875 US Patent Document 9,011,875	patent	April 2015
Mosaic clade M human immunodeficiency virus type 1 (HIV-1) gag immunogens Korber, Bette T.; Fischer, William M.; Letvin, Norman https://doi.org/https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/9044445 US Patent Document 9,044,445	patent	June 2015
Antigen Library Immunization Punnonen, Juha; Bass, Steven H.; Whalen, Robert Gerald https://doi.org/https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/20020198162 US Patent Document 09/247890; 20020198162	patent-application	December 2002
Enhanced first generation adenovirus vaccines expressing codon optimized HIV1-Gag, Pol, Nef and modifications Emini, Emilio A.; Youil, Rima; Bett, Andrew J. https://doi.org/https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/20030044421 US Patent Document 09/952060; 20030044421	patent-application	March 2003
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Polyvalent immunogen Haynes, Barton F.; Korber, Bette T.; De Lorimier, Robert M. https://doi.org/https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/20030147888 US Patent Document 10/289228; 20030147888	patent-application	August 2003
Immunogenic, cross-clade, HIV peptides DeGroot, Anne https://doi.org/https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/20030180314 US Patent Document 10/200708; 20030180314	patent-application	September 2003
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Polyvalent immunogen Haynes, Barton F.; Korber, Bette T.; De Lorimier, Robert M. https://doi.org/https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/20040001851 US Patent Document 10/373592; 20040001851	patent-application	January 2004
Ancestral and COT viral sequences, proteins and immunogenic compositions Mullins, James I.; Rodrigo, Allen G.; Learn, Gerald H. https://doi.org/https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/20050137387 US Patent Document 10/780507; 20050137387	patent-application	June 2005
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Polyvalent Vaccine Korber, Bette T.; Perkins, Simon; Bhattacharya, Tanmoy https://doi.org/https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/20090324631 US Patent Document 11/990222; 20090324631	patent-application	December 2009
Polyvalent Vaccine Korber, Bette; Perkins, Simon; Bhattacharya, Tanmoy https://doi.org/https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/20110150915 US Patent Application 12/960287; 20110150915	patent-application	June 2011
Polyvalent Vaccine Korber, Bette; Fischer, William; Letvin, Norman https://doi.org/https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/20120121631 US Patent Application 12/737761; 20120121631	patent-application	May 2012

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