Global Prevalence of Diabetes: Estimates for the year 2000 and projections for 2030
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April 2004 |
The Emerging Genetic Architecture of Type 2 Diabetes
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September 2008 |
Chronic high glucose induced INS-1β cell mitochondrial dysfunction: A comparative mitochondrial proteome with SILAC
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October 2013 |
Five Stages of Evolving Beta-Cell Dysfunction During Progression to Diabetes
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November 2004 |
Differentially Expressed Proteins in the Pancreas of Diet-induced Diabetic Mice
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September 2005 |
SH2B1 in -Cells Regulates Glucose Metabolism by Promoting -Cell Survival and Islet Expansion
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October 2013 |
Target-decoy search strategy for increased confidence in large-scale protein identifications by mass spectrometry
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February 2007 |
DAnTE: a statistical tool for quantitative analysis of -omics data
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May 2008 |
Haploid Insufficiency of Suppressor Enhancer Lin12 1-like (SEL1L) Protein Predisposes Mice to High Fat Diet-induced Hyperglycemia
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June 2011 |
Nucleobindin-2 Is a Positive Modulator of EGF-Dependent Signals Leading to Enhancement of Cell Growth and Suppression of Adipocyte Differentiation
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April 2012 |
A Simple Procedure for Effective Quenching of Trypsin Activity and Prevention of 18 O-Labeling Back-Exchange
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March 2009 |
Metabolic Diapause in Pancreatic β-Cells Expressing a Gain-of-function Mutant of the Forkhead Protein Foxo1
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January 2007 |
Small human islets comprised of more β -cells with higher insulin content than large islets
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March 2013 |
β-Cell deterioration during diabetes: what's in the gun?
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October 2009 |
Tissue-Specific Knockout of the Insulin Receptor in Pancreatic β Cells Creates an Insulin Secretory Defect Similar to that in Type 2 Diabetes
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February 1999 |
Improved LC−MS/MS Spectral Counting Statistics by Recovering Low-Scoring Spectra Matched to Confidently Identified Peptide Sequences
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November 2010 |
Preservation of β-cell function by targeting β-cell mass
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April 2008 |
Loss of Insulin Signaling in Hepatocytes Leads to Severe Insulin Resistance and Progressive Hepatic Dysfunction
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July 2000 |
Urocortin 3 Marks Mature Human Primary and Embryonic Stem Cell-Derived Pancreatic Alpha and Beta Cells
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December 2012 |
Increased Islet Volume but Unchanged Islet Number in ob/ob Mice
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July 2003 |
Proteomics Analysis of Cytokine-induced Dysfunction and Death in Insulin-producing INS-1E Cells: New Insights into the Pathways Involved
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October 2007 |
Peroxiredoxin 6, a Novel Player in the Pathogenesis of Diabetes
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June 2014 |
Detection of Differential Proteomes Associated with the Development of Type 2 Diabetes in the Zucker Rat Model Using the iTRAQ Technique
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February 2011 |
International Trial of the Edmonton Protocol for Islet Transplantation
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September 2006 |
Mechanisms of Compensatory -Cell Growth in Insulin-Resistant Rats: Roles of Akt Kinase
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July 2005 |
Insulin receptors in beta-cells are critical for islet compensatory growth response to insulin resistance
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April 2007 |
Modulation of the peroxiredoxin system by cytokines in insulin-producing RINm5F cells: Down-regulation of PRDX6 increases susceptibility of beta cells to oxidative stress
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July 2013 |
Usefulness of CDK5RAP3, CCNB2, and RAGE genes for the diagnosis of lung adenocarcinoma
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January 2007 |
18O-Labeled Proteome Reference as Global Internal Standards for Targeted Quantification by Selected Reaction Monitoring-Mass Spectrometry
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December 2011 |
Mechanism of compensatory hyperinsulinemia in normoglycemic insulin-resistant spontaneously hypertensive rats. Augmented enzymatic activity of glucokinase in beta-cells.
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July 1994 |
Nesfatin-1 stimulates glucagon and insulin secretion and beta cell NUCB2 is reduced in human type 2 diabetic subjects
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November 2011 |
Identification of nesfatin-1 as a satiety molecule in the hypothalamus
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October 2006 |
Differential Proteomic Analysis of the Pancreas of Diabetic db/db Mice Reveals the Proteins Involved in the Development of Complications of Diabetes Mellitus
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May 2014 |
Low insulin content of large islet population is present in situ and in isolated islets
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January 2011 |
Large-Scale Multiplexed Quantitative Discovery Proteomics Enabled by the Use of an 18 O-Labeled “Universal” Reference Sample
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January 2009 |
Altered function of insulin receptor substrate-1–deficient mouse islets and cultured β-cell lines
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December 1999 |
Sel1L is indispensable for mammalian endoplasmic reticulum-associated degradation, endoplasmic reticulum homeostasis, and survival
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January 2014 |
β-Cell Adaptation to Insulin Resistance
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October 2002 |
Adaptive β-cell proliferation increases early in high-fat feeding in mice, concurrent with metabolic changes, with induction of islet cyclin D2 expression
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July 2013 |
Antibody-free PRISM–SRM for multiplexed protein quantification: is this the new competition for immunoassays in bioanalysis?
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February 2013 |
Levels of the conversion endoproteases PC1 (PC3) and PC2 distinguish between insulin-producing pancreatic islet β cells and non-β cells
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May 1994 |
Pancreatic β Cell Dedifferentiation as a Mechanism of Diabetic β Cell Failure
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September 2012 |
Quantitative study of insulin secretion and clearance in normal and obese subjects.
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February 1988 |
Identification of the functional role of peroxiredoxin 6 in the progression of breast cancer
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November 2007 |
Functional beta-cell maturation is marked by an increased glucose threshold and by expression of urocortin 3
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February 2012 |
The Identification of Potential Factors Associated with the Development of Type 2 Diabetes
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August 2008 |
Advances in proteomics data analysis and display using an accurate mass and time tag approach
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January 2006 |
Role of the Saturated Nonesterified Fatty Acid Palmitate in Beta Cell Dysfunction
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December 2012 |
Reduced Progression of Diabetic Microvascular Complications With Islet Cell Transplantation Compared With Intensive Medical Therapy
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January 2011 |
Diet-Induced Obesity Causes Severe but Reversible Leptin Resistance in Arcuate Melanocortin Neurons
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March 2007 |
High Glucose Induces Dysfunction in Insulin Secretory Cells by Different Pathways: A Proteomic Approach
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December 2010 |
A Statistical Model for Identifying Proteins by Tandem Mass Spectrometry
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September 2003 |
Overexpression of a Novel Activator of PAK4, the CDK5 Kinase–Associated Protein CDK5RAP3, Promotes Hepatocellular Carcinoma Metastasis
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March 2011 |
Dietary-fat-induced obesity in mice results in beta cell hyperplasia but not increased insulin release: evidence for specificity of impaired beta cell adaptation
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June 2005 |
Development and Evaluation of a Micro- and Nanoscale Proteomic Sample Preparation Method
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December 2005 |
Antibody-free, targeted mass-spectrometric approach for quantification of proteins at low picogram per milliliter levels in human plasma/serum
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September 2012 |
Inhibition of Insulin Secretion as a New Drug Target in the Treatment of Metabolic Disorders
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June 2004 |
Nucleophosmin is essential for c-Myc nucleolar localization and c-Myc-mediated rDNA transcription
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June 2012 |
Alterations in the Glucose-Stimulated Insulin Secretory Dose-Response Curve and in Insulin Clearance in Nondiabetic Insulin-Resistant Individuals
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June 1997 |
Heterozygous SOD2 Deletion Impairs Glucose-Stimulated Insulin Secretion, but Not Insulin Action, in High-Fat–Fed Mice
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June 2014 |
Molecular and Metabolic Evidence for Mitochondrial Defects Associated With β-Cell Dysfunction in a Mouse Model of Type 2 Diabetes
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November 2009 |
Septins: the fourth component of the cytoskeleton
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February 2012 |
Growth factor control of pancreatic islet regeneration and function
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February 2009 |
Urocortin 3 regulates glucose-stimulated insulin secretion and energy homeostasis
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February 2007 |
Adaptation of islets of Langerhans to pregnancy: increased islet cell proliferation and insulin secretion correlates with the onset of placental lactogen secretion.
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March 1992 |
Spectral Probabilities and Generating Functions of Tandem Mass Spectra: A Strike against Decoy Databases
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August 2008 |
Mutational analysis of VAMP domains implicated in Ca2+-induced insulin exocytosis.
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December 1996 |
A dual population of islets of Langerhans in bovine pancreas
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February 1980 |
Peroxiredoxin III protects pancreatic β cells from apoptosis
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August 2010 |
VIPER: an advanced software package to support high-throughput LC-MS peptide identification
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June 2007 |
Development of a Novel Polygenic Model of NIDDM in Mice Heterozygous for IR and IRS-1 Null Alleles
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February 1997 |
Usefulness of CDK5RAP3, CCNB2 , and RAGE Genes for the Diagnosis of Lung Adenocarcinoma
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April 2007 |