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Regulated Antigen Expression in Live Recombinant Salmonella enterica Serovar Typhimurium Strongly Affects Colonization Capabilities and Specific CD4+-T-Cell Responses
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Characterization of recent H5 subtype avian influenza viruses from US poultry
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Trigger Factor Retards Protein Export in Escherichia coli
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Differential effect of auxotrophies on the release of macromolecules by Salmonella enterica vaccine strains
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Use of insertional inactivation to facilitate studies of biological properties of pneumococcal surface protein A (PspA)
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The Role of relA and spoT in Yersinia pestis KIM5+ Pathogenicity
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Epitope tagging of chromosomal genes in Salmonella
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YERSINIA OUTER PROTEINS: Role in Modulation of Host Cell Signaling Responses and Pathogenesis
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Biosynthesis and Assembly of Capsular Polysaccharides in Escherichia coli
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The Salmonella enterica serotype Typhi regulator TviA reduces interleukin-8 production in intestinal epithelial cells by repressing flagellin secretion
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A One-Plasmid System To Generate Influenza Virus in Cultured Chicken Cells for Potential Use in Influenza Vaccine
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Transcription Activation Parameters atara pBAD
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Antibacterial activity of Bacillus amyloliquefaciens phage endolysin without holin conjugation
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Immunization with the C‐Domain of α‐Toxin Prevents Lethal Infection, Localizes Tissue Injury, and Promotes Host Response to Challenge with Clostridium perfringens
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Genetic Loci of Major Antigenic Protein Genes of Edwardsiella tarda
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Defining epitopes: It's not as easy as it seems
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Salmonella Synthesizing 1-Monophosphorylated Lipopolysaccharide Exhibits Low Endotoxic Activity while Retaining Its Immunogenicity
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Salmonella as Live Trojan Horse for Vaccine Development and Cancer Gene Therapy
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Type 1/Type 2 Immunity in Infectious Diseases
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Sequence of the Genome of Salmonella Bacteriophage P22
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Live Attenuated Influenza Viruses Containing NS1 Truncations as Vaccine Candidates against H5N1 Highly Pathogenic Avian Influenza
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1918 Influenza: the Mother of All Pandemics
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Characterization of the Reconstructed 1918 Spanish Influenza Pandemic Virus
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Host and Bacterial Factors Contributing to the Clearance of Colonization by Streptococcus pneumoniae in a Murine Model
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RNA polymerase I catalysed transcription of insert viral cDNA
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A Regulatory Cascade in the Induction of rhaBAD
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The ATP-Dependent Lon Protease of Salmonella enterica Serovar Typhimurium Regulates Invasion and Expression of Genes Carried on Salmonella Pathogenicity Island 1
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Import of Plasmid DNA into the Nucleus Is Sequence Specific
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Incidence of Pneumococcal Disease Due to Non–Pneumococcal Conjugate Vaccine (PCV7) Serotypes in the United States during the Era of Widespread PCV7 Vaccination, 1998–2004
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“Ambisense” Approach for the Generation of Influenza A Virus: vRNA and mRNA Synthesis from One Template
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Macrophage-inducible expression of a model antigen in Salmonella typhimurium enhances immunogenicity.
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Diversity of PspA: Mosaic Genes and Evidence for Past Recombination in Streptococcus pneumoniae
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Multiple amino acid residues confer temperature sensitivity to human influenza virus vaccine strains (flumist) derived from cold-adapted a/ann arbor/6/60
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Immune responses dependent on antigen location in recombinant attenuated Salmonella typhimurium vaccines following oral immunization
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Immune Responses to Recombinant Pneumococcal PspA Antigen Delivered by Live Attenuated Salmonella enterica Serovar Typhimurium Vaccine
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Transduction-Mediated Transfer of Unmarked Deletion and Point Mutations through Use of Counterselectable Suicide Vectors
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Roles of the influenza virus polymerase and nucleoprotein in forming a functional RNP structure
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Regulated programmed lysis of recombinant Salmonella in host tissues to release protective antigens and confer biological containment
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A Recombinant Attenuated Salmonella enterica Serovar Typhimurium Vaccine Encoding Eimeria acervulina Antigen Offers Protection against E. acervulina Challenge
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Secretion of different listeriolysin cognates by recombinant attenuated Salmonella typhimurium: superior efficacy of haemolytic over non-haemolytic constructs after oral vaccination
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Evaluation of a phoP/phoQ-deleted, aroA-deleted live oral Salmonella typhi vaccine strain in human volunteers
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The inducible Iac operator-repressor system is functional in mammalian cells
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The inducible lac operator-repressor system is functional for control of expression of injected DNA in Xenopus oocytes
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Expression of a Porphyromonas gingivalis hemagglutinin on the surface of a Salmonella vaccine vector
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Effects of recJ, recQ, and recFOR Mutations on Recombination in Nuclease-Deficient recB recD Double Mutants of Escherichia coli
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Impact of intracellular location of and antigen display by intracellular bacteria: implications for vaccine development
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Immunogenicity and protective efficacy of DnaJ (hsp40) of Streptococcus pneumoniae against lethal infection in mice
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Expression of the low calcium response in Yersinia pestis
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Enhanced protective immunity against pneumococcal infection with PspA DNA and protein
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Upstream operators enhance repression of the lac promoter
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Repression oflacPromoter as a Function of Distance, Phase and Quality of an AuxiliarylacOperator
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Lac repressor and Lac operator
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Immunization of healthy adults with a single recombinant pneumococcal surface protein A (PspA) variant stimulates broadly cross-reactive antibodies to heterologous PspA molecules
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Antigen Sampling Across Epithelial Barriers and Induction of Mucosal Immune Responses
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Bacterial virulence, proinflammatory cytokines and host immunity: how to choose the appropriate Salmonella vaccine strain?
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Construction and Evaluation of a Dcya Dcrp Salmonella typhimurium Strain Expressing Avian Pathogenic Escherichia coli O78 LPS as a Vaccine to Prevent Airsacculitis in Chickens
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Development of Oral Vaccines to Stimulate Mucosal and Systemic Immunity: Barriers and Novel Strategies
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Anti-Polysaccharide Immunoglobulin Isotype Levels and Opsonic Activity of Antisera: Relationships with Protection against Streptococcus pneumoniae Infection in Mice
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Intranasal Vaccination with Pneumococcal Surface Protein A and Interleukin-12 Augments Antibody-Mediated Opsonization and Protective Immunity against Streptococcus pneumoniae Infection
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Breaking through the acid barrier: An orchestrated response to proton stress by enteric bacteria
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The Complete Genome Sequence of Escherichia coli K-12
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Oral Vaccination with Different Antigens from Yersinia pestis KIM Delivered by Live Attenuated Salmonella Typhimurium Elicits a Protective Immune Response Against Plague
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The potential for using protein vaccines to protect against otitis media caused by Streptococcus pneumoniae
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Interleukin-10 and Inhibition of Innate Immunity to Yersiniae: Roles of Yops and LcrV (V Antigen)
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Salmonella redirects phagosomal maturation
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Use of the nirB Promoter to Direct the Stable Expression of Heterologous Antigens in Salmonella Oral Vaccine Strains: Development of a Single–Dose Oral Tetanus Vaccine
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Simultaneous Analyses of Neutral Carbohydrates and Amino Sugars in Freshwaters with HPLC-PAD
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The ACT domain family
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One-step inactivation of chromosomal genes in Escherichia coli K-12 using PCR products
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Towards safer vectors for the field release of recombinant bacteria
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Homocysteine Antagonism of Nitric Oxide-Related Cytostasis in Salmonella typhimurium
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Bacteriology of acute otitis media: A new perspective
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Genome Sequence of Yersinia pestis KIM
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DNA Uptake in Bacteria
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How Salmonella Survive Against the Odds
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Can a ‘flawless’ live vector vaccine strain be engineered?
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The Use of Live Attenuated Bacteria as a Delivery System for Heterologous Antigens
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recB recJ mutants ofSalmonella typhimurium are deficient in transductional recombination, DNA repair and plasmid maintenance
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The E. coli α-hemolysin secretion system and its use in vaccine development
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Gastric Acidity and Cholera
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Characterization of the Yersinia pestis Yfu ABC Inorganic Iron Transport System
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Magnitude and Impact of Diarrheal Diseases
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Identification and molecular analysis of glgS, a novel growth-phase-regulated and rpoS-dependent gene involved in glycogen synthesis in Escherichia coli
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Avirulent microbes and uses therefor: salmonella typhi
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Avirulent microbes and uses therefor: Salmonella typhi
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Avirulent microbes and uses therefor
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Vaccines containing avirulent phop-type microorganisms
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Avirulent microbes and uses therefor
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Chondroitinase attenuated Edwardsiella ictaluri and a vaccine for prevention of enteric septicemia (es) in fish
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Oral immunization by transgenic plants
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Recombinant avirulent salmonella antifertility vaccines
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Selective maintenance of a recombinant gene in a population of vaccine cells
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September 1997 |
Oral immunization by transgenic plants
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Oral immunization by transgenic plants
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Clostridium perfringens vaccines
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Molecule and method for importing DNA into a nucleus
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Method of maintaining a desired recombinant gene in a genetic population of cells
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Avirulent microbes and uses therefor
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Avirulent microbes and uses therefor
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Stable pura vectors and uses therefor
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patent
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Recombinant avirulent immunogenic S typhi having rpos positive phenotype
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DNA based vaccination of fish
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Parasitic helminth cuticlin nucleic acid molecules and uses thereof
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Attenuated Pasteurella piscicida vaccine for fish
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Recombinant vaccines comprising immunogenic attenuated bacteria having RPOS positive phenotype
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Live attenuated salmonella vaccines to control avian pathogens
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Clostridium perfringens vaccines
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Recombinant bacterial system with environmentally limited viability
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Regulated antigen delivery system (RADS)
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Functional balanced-lethal host-vector systems
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Plasmid maintenance system for antigen delivery
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Recombinant vaccines comprising immunogenic attenuated bacteria having RpoS positive phenotype
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Modulation of immune responses to foreign antigens expressed by recombinant attenuated bacterial vectors
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Mixed Virus-like particles
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April 2007 |
Regulated antigen delivery system (RADS)
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patent
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Recombinant bacterial vaccine system with environmentally limited viability
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Recombinant influenza vectors with tandem transcription units
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Regulated attenuation of live vaccines to enhance cross-protective immunogenicity
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Regulated expression of antigen and/or regulated attentuation to enhance vaccine immunogenicity and/or safety
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patent
|
May 2013 |
Recombinant bacterium capable of eliciting an immune response against enteric pathogens
|
patent
|
June 2013 |
Use of genes for increasing the oil content in plants
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patent-application
|
September 2006 |
Methods and Compositions Related to Thioesterase Enzymes
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patent-application
|
June 2010 |