Combining Multiple Pairwise Structure-based Alignments

Software · Wed Nov 12 00:00:00 EST 2014

OSTI ID:1232074

CombAlign is a new Python code that generates a gapped, one-to-many, multiple structure-based sequence alignment(MSSA) given a set of pairwise structure-based alignments. In order to better define regions of similarity among related protein structures, it is useful to detect the residue-residue correspondences among a set of pairwise structure alignments. Few codes exist for constructing a one-to-many, multiple sequence alignment derived from a set of structure alignments, and we perceived a need for creating a new tool for combing pairwise structure alignments that would allow for insertion of gaps in the reference structure.

• Short Name / Acronym: COMBALIGN; 003359WKSTN00
• Site Accession Number: LLNL-CODE-667658
• Version: 00
• Programming Language(s): Medium: X; OS: Linux RedHat 6.5; Compatibility: Workstation
• Research Organization: Lawrence Livermore National Laboratory (LLNL), Livermore, CA (United States)
• Sponsoring Organization: USDOE
• Contributing Organization: C. L. Ecale Zhou
• DOE Contract Number: AC52-07NA27344
• OSTI ID: 1232074
• Country of Origin: United States