skip to main content
OSTI.GOV title logo U.S. Department of Energy
Office of Scientific and Technical Information

Title: Multifunctional thin film surface

Patent ·
OSTI ID:1223108
; ; ; ; ;

A thin film with multiple binding functionality can be prepared on an electrode surface via consecutive electroreduction of two or more aryl-onium salts with different functional groups. This versatile and simple method for forming multifunctional surfaces provides an effective means for immobilization of diverse molecules at close proximities. The multifunctional thin film has applications in bioelectronics, molecular electronics, clinical diagnostics, and chemical and biological sensing.

Research Organization:
Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)
Sponsoring Organization:
USDOE
DOE Contract Number:
AC04-94AL85000
Assignee:
Sandia Corporation (Albuquerque, NM)
Patent Number(s):
9,157,161
Application Number:
13/183,099
OSTI ID:
1223108
Resource Relation:
Patent File Date: 2011 Jul 14
Country of Publication:
United States
Language:
English

References (40)

Methods and devices for carrying out chemical reactions patent June 2001
Analytical instruments, biosensors and methods thereof patent November 2003
Electrochemical assembly of organic molecules by the reduction of iodonium salts patent June 2009
Method for grafting and growing a conductive organic film on a surface patent-application December 2004
Diazonium−Protein Adducts for Graphite Electrode Microarrays Modification:  Direct and Addressed Electrochemical Immobilization journal December 2005
Diazonium salts: Stable monolayers on gold electrodes for sensing applications journal February 2007
Covalent modification of carbon surfaces by grafting of functionalized aryl radicals produced from electrochemical reduction of diazonium salts journal July 1992
Formation of Multilayers on Glassy Carbon Electrodes via the Reduction of Diazonium Salts journal September 2001
Immobilization of Glycosylated Enzymes on Carbon Electrodes, and its Application in Biosensors journal April 2005
Immobilization of Aryl and Alkynyl Groups onto Glassy Carbon Surfaces by Electrochemical Reduction of Iodonium Salts journal August 2005
Covalent Grafting of Glassy Carbon Electrodes with Diaryliodonium Salts:  New Aspects journal March 2007
Anti-Sticking Effect of Organic Dielectric Formed by Electrodeposition in Microelectromechanical-System Structures journal July 2005
Electrochemical Surface Derivatization of Glassy Carbon by the Reduction of Triaryl- and Alkyldiphenylsulfonium Salts journal January 2008
Direct electrochemistry of horseradish peroxidase bonded on a conducting polymer modified glassy carbon electrode journal November 2003
Immobilization of glucose oxidase on a carbon surface derivatized by electrochemical reduction of diazonium salts journal September 1992
Biotinylation of Screen-Printed Carbon Electrodes through the Electrochemical Reduction of the Diazonium Salt of p -Aminobenzoyl Biocytin journal July 1999
Electroaddressable Selective Functionalization of Electrode Arrays: Catalytic NADH Detection Using Aryl Diazonium Modified Gold Electrodes journal June 2007
Protein Pattern Assembly by Active Control of a Triblock Copolymer Monolayer journal December 2006
DNA immobilization onto electrochemically functionalized Si(100) surfaces journal October 2006
Multifunctional Electrode Arrays: Towards a Universal Detection Platform journal March 2008
Enzyme Based Amperometric Biosensors for Food Analysis journal February 2002
Biomolecule immobilization on electrode surfaces by entrapment or attachment to electrochemically polymerized films. A review journal May 1999
Direct electrical communication between chemically modified enzymes and metal electrodes. 2. Methods for bonding electron-transfer relays to glucose oxidase and D-amino-acid oxidase journal April 1988
Characterization of the Deposition of Organic Molecules at the Surface of Gold by the Electrochemical Reduction of Aryldiazonium Cations journal July 2005
Electrically Addressable Biomolecular Functionalization of Carbon Nanotube and Carbon Nanofiber Electrodes journal September 2004
An Interface Comprising Molecular Wires and Poly(ethylene glycol) Spacer Units Self-Assembled on Carbon Electrodes for Studies of Protein Electrochemistry journal August 2006
Universal tools for biomolecular attachment to surfaces journal November 2006
Diazonium-Functionalized Horseradish Peroxidase Immobilized via Addressable Electrodeposition:  Direct Electron Transfer and Electrochemical Detection journal January 2007
Direct Covalent Grafting of Conjugated Molecules onto Si, GaAs, and Pd Surfaces from Aryldiazonium Salts
  • Stewart, Michael P.; Maya, Francisco; Kosynkin, Dmitry V.
  • Journal of the American Chemical Society, Vol. 126, Issue 1, p. 370-378 https://doi.org/10.1021/ja0383120
journal January 2004
Formation of Polyphenylene Films on Metal Electrodes by Electrochemical Reduction of Benzenediazonium Salts journal April 2006
Covalent Modification of Carbon Surfaces by Aryl Radicals Generated from the Electrochemical Reduction of Diazonium Salts journal January 1997
Mono- and Multilayer Formation by Diazonium Reduction on Carbon Surfaces Monitored with Atomic Force Microscopy “Scratching” journal August 2003
Organic Layers Bonded to Industrial, Coinage, and Noble Metals through Electrochemical Reduction of Aryldiazonium Salts journal September 2003
Multilayer Nitroazobenzene Films Covalently Attached to Carbon. An AFM and Electrochemical Study journal May 2005
Nanoscale Patterning of Flat Carbon Surfaces by Scanning Probe Lithography and Electrochemistry journal March 2005
Microscale Patterning of Organic Films on Carbon Surfaces Using Electrochemistry and Soft Lithography † journal December 2006
A Multifunctional Thin Film Au Electrode Surface Formed by Consecutive Electrochemical Reduction of Aryl Diazonium Salts journal March 2009
The modification of glassy carbon and gold electrodes with aryl diazonium salt: The impact of the electrode materials on the rate of heterogeneous electron transfer journal December 2005
The Electrochemical Grafting of a Mixture of Substituted Phenyl Groups at a Glassy Carbon Electrode Surface journal June 2008
Modified Carbon Surfaces as “Organic Electrodes” That Exhibit Conductance Switching journal January 2003

Similar Records

Related Subjects

47 OTHER INSTRUMENTATION