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Title: Injectible bodily prosthetics employing methacrylic copolymer gels

Patent ·
OSTI ID:1176127

The present invention provides novel block copolymers as structural supplements for injectible bodily prosthetics employed in medical or cosmetic procedures. The invention also includes the use of such block copolymers as nucleus pulposus replacement materials for the treatment of degenerative disc disorders and spinal injuries. The copolymers are constructed by polymerization of a tertiary amine methacrylate with either a (poly(ethylene oxide)-b-poly(propylene oxide)-b-poly(ethylene oxide) polymer, such as the commercially available Pluronic.RTM. polymers, or a poly(ethylene glycol) methyl ether polymer.

Research Organization:
Ames Laboratory (AMES), Ames, IA (United States)
Sponsoring Organization:
USDOE
DOE Contract Number:
W-7405-ENG-82
Assignee:
Iowa State University Research Foundation, Inc. (Ames, IA)
Patent Number(s):
7,183,369
Application Number:
10/367,414
OSTI ID:
1176127
Resource Relation:
Patent File Date: 2003 Feb 14
Country of Publication:
United States
Language:
English

References (3)

Synthesis of Controlled Structure Water-Soluble Diblock Copolymers via Oxyanionic Polymerization journal March 1999
Food Authenticity journal May 2001
Structure of pH-Dependent Block Copolymer Micelles:  Charge and Ionic Strength Dependence journal October 2002